CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
41 results for "CTLA-4" in Products
41 results for "CTLA-4" in Products
CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, CyTOF-ready, ICC |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, Flow, IP |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #PS01-34 |
| Applications: | IHC |
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, Flow, IP |
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, Flow, IP |
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, ICC/IF, Flow, IP |
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, ICC/IF, Flow, IP |
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, ICC/IF, Flow, IP |
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, ICC/IF, Flow, IP |
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, ICC/IF, Flow, IP |
![CTLA-4 Antibody (1B8) [Allophycocyanin]](https://resources.bio-techne.com/images/products/nbp1-41000apc_armenian-hamster-monoclonal-ctla-4-antibody-1b8-allophycocyanin-31720239534961.jpg "CTLA-4 Antibody (1B8) [Allophycocyanin] [NBP1-41000APC] -")
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, ICC/IF, Flow, IP |
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, ICC/IF, Flow, IP |
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, ICC/IF, Flow, IP |
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, ICC/IF, Flow, IP |
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, ICC/IF, Flow, IP |
![CTLA-4 Antibody (1B8) [Alexa Fluor® 405]](https://resources.bio-techne.com/images/products/nbp1-41000af405_armenian-hamster-monoclonal-ctla-4-antibody-1b8-alexa-fluor-405-3172023913653.jpg "CTLA-4 Antibody (1B8) [Alexa Fluor® 405] [NBP1-41000AF405] -")
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, ICC/IF, Flow, IP |
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, ICC/IF, Flow, IP |
![CTLA-4 Antibody (1B8) [mFluor Violet 610 SE]](https://resources.bio-techne.com/images/products/nbp1-41000mfv610_armenian-hamster-ctla-4-mab-1b8-mfluor-violet-610-se-5720231581819.png "CTLA-4 Antibody (1B8) [mFluor Violet 610 SE] [NBP1-41000MFV610] -")
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, ICC/IF, Flow, IP |
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, ICC/IF, Flow, IP |
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, ICC/IF, Flow, IP |