CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
51 results for "CTLA-4" in Products
51 results for "CTLA-4" in Products
CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, ICC/IF, ELISA, Flow, IP |
![CTLA-4 Antibody (BNI3) ELISA: CTLA-4 Antibody (BNI3) [NB100-64849] -](https://resources.bio-techne.com/images/products/nb100-64849_mouse-monoclonal-ctla-4-antibody-bni3-2312025235988.jpg "ELISA: CTLA-4 Antibody (BNI3) [NB100-64849] -")
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, ELISA, ICC/IF, Flow, IP |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #63828 |
| Applications: | WB, Flow, CyTOF-ready, B/N |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #63828 |
| Applications: | WB, Flow, CyTOF-ready, B/N |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, ELISA, ICC/IF, Flow, IP |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #63828 |
| Applications: | WB, Flow, CyTOF-ready, B/N |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #63828 |
| Applications: | WB, Flow, CyTOF-ready, B/N |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #63828 |
| Applications: | WB, Flow, CyTOF-ready, B/N |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, Flow, IP |
![CTLA-4 Antibody (BNI3) [Alexa Fluor® 488]](https://resources.bio-techne.com/images/products/nb100-64849af488_mouse-ctla-4-mab-bni3-alexa-fluor-488-25720231524750.jpg "CTLA-4 Antibody (BNI3) [Alexa Fluor® 488] [NB100-64849AF488] -")
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #63828 |
| Applications: | WB, Flow, CyTOF-ready, B/N |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, Flow, IP |
![CTLA-4 Antibody (BNI3) [Alexa Fluor® 405]](https://resources.bio-techne.com/images/products/nb100-64849af405_mouse-ctla-4-mab-bni3-alexa-fluor-405-317202391584.jpg "CTLA-4 Antibody (BNI3) [Alexa Fluor® 405] [NB100-64849AF405] -")
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #63828 |
| Applications: | WB, Flow, CyTOF-ready, B/N |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, Flow, IP |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #63828 |
| Applications: | WB, Flow, CyTOF-ready, B/N |
![CTLA-4 Antibody (63828) [Alexa Fluor® 532]](https://resources.bio-techne.com/images/products/fab434x_rat-monoclonal-ctla-4-antibody-63828-alexa-fluor-532-3172023823243.jpg "CTLA-4 Antibody (63828) [Alexa Fluor® 532] [FAB434X] -")
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, Flow, IP |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #63828 |
| Applications: | WB, Flow, CyTOF-ready, B/N |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, Flow, IP |
![CTLA-4 Antibody (BNI3) [FITC]](https://resources.bio-techne.com/images/products/nb100-64849f_mouse-ctla-4-mab-bni3-fitc-31720238133419.jpg "CTLA-4 Antibody (BNI3) [FITC] [NB100-64849F] -")
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, Flow, IP |
![CTLA-4 Antibody (BNI3) [mFluor Violet 610 SE]](https://resources.bio-techne.com/images/products/nb100-64849mfv610_mouse-ctla-4-mab-bni3-mfluor-violet-610-se-57202315345937.png "CTLA-4 Antibody (BNI3) [mFluor Violet 610 SE] [NB100-64849MFV610] -")
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, Flow, IP |
![CTLA-4 Antibody (BNI3) [Alexa Fluor® 647]](https://resources.bio-techne.com/images/products/nb100-64849af647_mouse-ctla-4-mab-bni3-alexa-fluor-647-2472023112136.jpg "CTLA-4 Antibody (BNI3) [Alexa Fluor® 647] [NB100-64849AF647] -")
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, Flow, IP |
![CTLA-4 Antibody (BNI3) [Alexa Fluor® 700]](https://resources.bio-techne.com/images/products/nb100-64849af700_mouse-ctla-4-mab-bni3-alexa-fluor-700-317202398447.jpg "CTLA-4 Antibody (BNI3) [Alexa Fluor® 700] [NB100-64849AF700] -")
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #63828 |
| Applications: | WB, Flow, CyTOF-ready, B/N |