CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
198 results for "CTLA-4" in Products
198 results for "CTLA-4" in Products
CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
Reactivity: | Mouse |
Details: | Rat IgG2A Monoclonal Clone #63828 |
Applications: | WB, Flow, CyTOF-ready, B/N |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Kappa Monoclonal Clone #9H10 |
Applications: | WB, ELISA, Flow, B/N |
Reactivity: | Mouse |
Details: | Rat IgG2A Monoclonal Clone #63828 |
Applications: | WB, Flow, CyTOF-ready, B/N |
Reactivity: | Mouse |
Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
Applications: | WB, ELISA, Flow, IP |
Reactivity: | Mouse |
Details: | Rat IgG2A Monoclonal Clone #63828 |
Applications: | WB, Flow, CyTOF-ready, B/N |
Reactivity: | Mouse |
Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
Applications: | WB, ELISA, Flow, IP |
Reactivity: | Human, Mouse, Rat, Bovine |
Details: | Mouse IgG1 kappa Monoclonal Clone #L4P2F5*F10 |
Applications: | IHC, WB, ELISA |
Reactivity: | Mouse |
Details: | Rat IgG2A Monoclonal Clone #63828 |
Applications: | WB, Flow, CyTOF-ready, B/N |
Reactivity: | Human, Mouse, Rat, Bovine |
Details: | Mouse IgG1 kappa Monoclonal Clone #L4P2F5*F10 |
Applications: | IHC, WB, ELISA |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Armenian Hamster IgG Kappa Monoclonal Clone #9H10 |
Applications: | WB, ELISA, Flow, B/N |
Reactivity: | Human, Mouse |
Details: | Mouse Monoclonal Clone #37B3D8.2F2 |
Applications: | WB |
Reactivity: | Mouse |
Details: | Rat IgG2A Monoclonal Clone #63828 |
Applications: | WB, Flow, CyTOF-ready, B/N |
Reactivity: | Human, Mouse |
Details: | Mouse Monoclonal Clone #37B3D8.2F2 |
Applications: | WB |
Reactivity: | Mouse |
Details: | Rat IgG2A Monoclonal Clone #63828 |
Applications: | WB, Flow, CyTOF-ready, B/N |
Reactivity: | Mouse |
Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
Applications: | WB, ELISA, ICC/IF, Flow, IP |
Recombinant Monoclonal Antibody
Reactivity: | Mouse |
Details: | Rabbit IgG Kappa Monoclonal Clone #9H10 |
Applications: | WB, ELISA, Flow, B/N |
Reactivity: | Mouse |
Details: | Rat IgG2 Monoclonal Clone #RM0199-6G10 |
Applications: | WB, Flow, CyTOF-ready, B/N |
Reactivity: | Mouse |
Details: | Rat IgG2A Monoclonal Clone #63828 |
Applications: | WB, Flow, CyTOF-ready, B/N |
Reactivity: | Mouse |
Details: | Rat IgG2 Monoclonal Clone #RM0199-6G10 |
Applications: | WB, Flow, CyTOF-ready, B/N |
Reactivity: | Mouse |
Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
Applications: | WB, ELISA, ICC/IF, Flow, IP |
Reactivity: | Human, Mouse |
Details: | Mouse Monoclonal Clone #37B3D8.2F2 |
Applications: | WB |
Reactivity: | Human, Mouse |
Details: | Mouse Monoclonal Clone #37B3D8.2F2 |
Applications: | WB |
Reactivity: | Human, Mouse |
Details: | Mouse Monoclonal Clone #37B3D8.2F2 |
Applications: | WB |
Reactivity: | Human, Mouse |
Details: | Mouse Monoclonal Clone #37B3D8.2F2 |
Applications: | WB |
Reactivity: | Human, Mouse |
Details: | Mouse Monoclonal Clone #37B3D8.2F2 |
Applications: | WB |