Dkk-3 Products
Dkk-3, also known as REIC, is a member of the Dickkopf family of secreted Wnt antagonists. Dkk-3 is expressed most strongly in the adult heart, brain, and spinal cord as well as during early embryonic development. Dkk-3 is downregulated in many tumors which often is correlated with faster tumor progression and shorter survival. The prototype Dickkopf member, Dkk-1, antagonizes Wnt family signaling by binding to Wnt receptors LRP5 and LRP6 (low-density lipoprotein receptor-related proteins) and promoting their internalization. In contrast, Dkk-3 may either promote or inhibit Wnt signaling.
Products:
87 results for "Dkk-3" in Products
87 results for "Dkk-3" in Products
Dkk-3 Products
Dkk-3, also known as REIC, is a member of the Dickkopf family of secreted Wnt antagonists. Dkk-3 is expressed most strongly in the adult heart, brain, and spinal cord as well as during early embryonic development. Dkk-3 is downregulated in many tumors which often is correlated with faster tumor progression and shorter survival. The prototype Dickkopf member, Dkk-1, antagonizes Wnt family signaling by binding to Wnt receptors LRP5 and LRP6 (low-density lipoprotein receptor-related proteins) and promoting their internalization. In contrast, Dkk-3 may either promote or inhibit Wnt signaling.
Products:
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | ELISA, IHC |
| Source: | NS0 |
| Accession #: | Q9UBP4.1 |
| Applications: | BA |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #138728 |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #8A5C6 |
| Applications: | IHC, WB, ELISA, Flow, CyTOF-ready |
![Western Blot: Dkk-3 Antibody (8A5C6)BSA Free [NBP2-37430]](https://resources.bio-techne.com/images/products/Dkk-3-Antibody-8A5C6-Western-Blot-NBP2-37430-img0003.jpg "Western Blot: Dkk-3 Antibody (8A5C6)BSA Free [NBP2-37430]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #138726 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Dkk-3 Antibody [NBP1-80843]](https://resources.bio-techne.com/images/products/Dkk-3-Antibody-Western-Blot-NBP1-80843-img0006.jpg "Western Blot: Dkk-3 Antibody [NBP1-80843]")
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #153103 |
| Applications: | WB |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR2053 |
| Applications: | WB, ICC/IF, IP |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #1R5E0 |
| Applications: | WB, ICC/IF |
![Western Blot: Dkk-3 Antibody (1R5E0) [NBP3-16293]](https://resources.bio-techne.com/images/products/Dkk-3-Antibody-1R5E0-Western-Blot-NBP3-16293-img0002.jpg "Western Blot: Dkk-3 Antibody (1R5E0) [NBP3-16293]")
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #019 |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: Dkk-3 Antibody [NB100-899]](https://resources.bio-techne.com/images/products/Dkk-3-Antibody-Western-Blot-NB100-899-img0001.jpg "Western Blot: Dkk-3 Antibody [NB100-899]")
| Applications: | WB |
![Western Blot: Dkk-3 Overexpression Lysate [NBP2-09162]](https://resources.bio-techne.com/images/products/DKK3-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-09162-img0001.jpg "Western Blot: Dkk-3 Overexpression Lysate [NBP2-09162]")
| Applications: | WB |
![Western Blot: Dkk-3 Overexpression Lysate [NBL1-09903]](https://resources.bio-techne.com/images/products/DKK3-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-09903-img0002.jpg "Western Blot: Dkk-3 Overexpression Lysate [NBL1-09903]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #103B5 |
| Applications: | WB, ELISA |
![Western Blot: Dkk-3 Antibody (103B5)BSA Free [NBP2-60242]](https://resources.bio-techne.com/images/products/Dkk-3-Antibody-103B5-Western-Blot-NBP2-60242-img0001.jpg "Western Blot: Dkk-3 Antibody (103B5)BSA Free [NBP2-60242]")
| Applications: | WB |
![Western Blot: Dkk-3 Overexpression Lysate [NBL1-09904]](https://resources.bio-techne.com/images/products/DKK3-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-09904-img0002.jpg "Western Blot: Dkk-3 Overexpression Lysate [NBL1-09904]")
| Applications: | ELISA |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #019 |
| Applications: | ELISA |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #103B5 |
| Applications: | WB, ELISA |