Endoglin/CD105 Products
Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.
65 results for "Endoglin/CD105" in Products
65 results for "Endoglin/CD105" in Products
Endoglin/CD105 Products
Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, Flow, IHC, CyTOF-ready, +1 More |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #209701 |
| Applications: | WB, Flow, IHC, CyTOF-ready, ICC |
| Sensitivity: | 13.6 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #3A9 |
| Applications: | IHC, WB, ICC/IF, ELISA |
![Western Blot: Endoglin/CD105 Antibody (3A9)BSA Free [NBP2-22122]](https://resources.bio-techne.com/images/products/Endoglin-CD105-Antibody-3A9-Western-Blot-NBP2-22122-img0006.jpg "Western Blot: Endoglin/CD105 Antibody (3A9)BSA Free [NBP2-22122]")
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC |
| Reactivity: | Mouse, Rat |
| Details: | Rat IgG2a Kappa Monoclonal Clone #MJ7/18 |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
![Western Blot: Endoglin/CD105 Antibody (MJ7/18) [NB100-77666]](https://resources.bio-techne.com/images/products/Endoglin-CD105-Antibody-MJ7-18-Western-Blot-NB100-77666-img0001.jpg "Western Blot: Endoglin/CD105 Antibody (MJ7/18) [NB100-77666]")
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #209701 |
| Applications: | Flow |
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Source: | NS0 |
| Accession #: | Q8K100 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #209721 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #209701 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #209701 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #209701 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #209701 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #209701 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #209701 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #209701 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #209701 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #209701 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #209701 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #3A9 |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Kappa Monoclonal Clone #MJ7/18 |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Kappa Monoclonal Clone #MJ7/18 |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Kappa Monoclonal Clone #MJ7/18 |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #209701 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready |