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gp130 Products

Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.

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37 results for "gp130" in Products

37 results for "gp130" in Products

gp130 Products

Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.

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Applications: WB, Flow, CyTOF-ready
Reactivity: Mouse
Applications: Flow, CyTOF-ready, ICC
Reactivity: Mouse
Applications: Flow
Reactivity: Mouse
Applications: Neut
Reactivity: Mouse
Applications: Flow, ICC
Reactivity: Mouse
Applications: Flow
Reactivity: Mouse
Applications: WB
Reactivity: Mouse
Applications: WB, Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Mouse

Recombinant Monoclonal Antibody

Applications: ICC/IF, Flow, CyTOF-ready
Reactivity: Mouse
Applications: ICC/IF, Flow, CyTOF-ready
Reactivity: Mouse
Applications: Flow
Reactivity: Mouse

Recombinant Monoclonal Antibody

Applications: ICC/IF, Flow, CyTOF-ready
Reactivity: Mouse
Applications: ICC/IF, Flow, CyTOF-ready
Reactivity: Mouse
Applications: ICC/IF, Flow, CyTOF-ready
Reactivity: Mouse
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