GRK1 Products
G protein-coupled receptor kinases (GRKs) are important modulators of G protein-coupled receptor (GPCR) signaling. Receptor phosphorylation by specific GRKs plays a key role in triggering rapid desensitization. The GRK family consists of 7 isoforms that share a central catalytic domain with homology to other serine/threonine kinases. The catalytic domain is flanked by an amino-terminal RGS domain of 183 - 188 amino acids and a carboxyl-terminus of variable length. GRK1 and GRK7 are members of the rhodopsin kinase or visual GRK subfamily.
70 results for "GRK1" in Products
70 results for "GRK1" in Products
GRK1 Products
G protein-coupled receptor kinases (GRKs) are important modulators of G protein-coupled receptor (GPCR) signaling. Receptor phosphorylation by specific GRKs plays a key role in triggering rapid desensitization. The GRK family consists of 7 isoforms that share a central catalytic domain with homology to other serine/threonine kinases. The catalytic domain is flanked by an amino-terminal RGS domain of 183 - 188 amino acids and a carboxyl-terminus of variable length. GRK1 and GRK7 are members of the rhodopsin kinase or visual GRK subfamily.
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #466630 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Monkey, Primate - Macaca mulatta (Rhesus Macaque) |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55226]](https://resources.bio-techne.com/images/products/GRK1-Antibody-Immunohistochemistry-Paraffin-NBP2-55226-img0008.jpg "Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55226]")
| Reactivity: | Human, Mouse, Rat, Bovine, Chicken |
| Details: | Mouse IgG1 Monoclonal Clone #G8 |
| Applications: | WB, ICC/IF, IP |
![Immunocytochemistry/ Immunofluorescence: GRK1 Antibody (G8) - BSA Free [NB120-2775]](https://resources.bio-techne.com/images/products/GRK1-Antibody-G8-Immunocytochemistry-Immunofluorescence-NB120-2775-img0009.jpg "Immunocytochemistry/ Immunofluorescence: GRK1 Antibody (G8) - BSA Free [NB120-2775]")
| Reactivity: | Human, Bovine |
| Details: | Mouse IgG1 Monoclonal Clone #D11 |
| Applications: | IHC, WB, ICC/IF, IP |
![Immunocytochemistry/ Immunofluorescence: GRK1 Antibody (D11) - BSA Free [NB120-2776]](https://resources.bio-techne.com/images/products/GRK1-Antibody-D11-Immunocytochemistry-Immunofluorescence-NB120-2776-img0009.jpg "Immunocytochemistry/ Immunofluorescence: GRK1 Antibody (D11) - BSA Free [NB120-2776]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55732]](https://resources.bio-techne.com/images/products/GRK1-Antibody-Immunohistochemistry-Paraffin-NBP2-55732-img0007.jpg "Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55732]")
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #1G8 |
| Applications: | WB, ELISA |
| Applications: | WB |
![Western Blot: GRK1 Overexpression Lysate [NBL1-11342]](https://resources.bio-techne.com/images/products/GRK1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-11342-img0002.jpg "Western Blot: GRK1 Overexpression Lysate [NBL1-11342]")
| Reactivity: | Human, Bovine |
| Details: | Mouse IgG1 Monoclonal Clone #D11 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Human, Mouse, Rat, Bovine, Chicken |
| Details: | Mouse IgG1 Monoclonal Clone #G8 |
| Applications: | WB, ICC/IF, IP |
| Applications: | AC |
| Applications: | AC |
| Reactivity: | Human, Bovine |
| Details: | Mouse IgG1 Monoclonal Clone #D11 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Human, Bovine |
| Details: | Mouse IgG1 Monoclonal Clone #D11 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Human, Bovine |
| Details: | Mouse IgG1 Monoclonal Clone #D11 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Human, Bovine |
| Details: | Mouse IgG1 Monoclonal Clone #D11 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Human, Mouse, Rat, Bovine, Chicken |
| Details: | Mouse IgG1 Monoclonal Clone #G8 |
| Applications: | WB, ICC/IF, IP |
| Reactivity: | Human, Mouse, Rat, Bovine, Chicken |
| Details: | Mouse IgG1 Monoclonal Clone #G8 |
| Applications: | WB, ICC/IF, IP |
| Reactivity: | Human, Mouse, Rat, Bovine, Chicken |
| Details: | Mouse IgG1 Monoclonal Clone #G8 |
| Applications: | WB, ICC/IF, IP |
| Reactivity: | Human, Mouse, Rat, Bovine, Chicken |
| Details: | Mouse IgG1 Monoclonal Clone #G8 |
| Applications: | WB, ICC/IF, IP |
Potent and selective GRK2/3 inhibitor
| Chemical Name: | 3-[[[4-Methyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]methyl]amino]-N-[[2-(trifluoromethyl)phenyl]methyl]benzamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat, Bovine, Chicken |
| Details: | Mouse IgG1 Monoclonal Clone #G8 |
| Applications: | WB, ICC/IF, IP |
| Reactivity: | Human, Bovine |
| Details: | Mouse IgG1 Monoclonal Clone #D11 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Human, Bovine |
| Details: | Mouse IgG1 Monoclonal Clone #D11 |
| Applications: | IHC, WB, ICC/IF, IP |