GRK3 Products
G protein-coupled receptor kinases (GRKs) are important modulators of G protein-coupled receptor (GPCR) signaling. Receptor phosphorylation by specific GRKs plays a key role in triggering rapid desensitization. The GRK family consists of 7 isoforms that share a central catalytic domain with homology to other serine/threonine kinases. The catalytic domain is flanked by an amino-terminal RGS domain of 183 - 188 amino acids and a carboxyl-terminus of variable length. GRK1 and GRK7 are members of the rhodopsin kinase or visual GRK subfamily.
12 results for "GRK3" in Products
12 results for "GRK3" in Products
GRK3 Products
G protein-coupled receptor kinases (GRKs) are important modulators of G protein-coupled receptor (GPCR) signaling. Receptor phosphorylation by specific GRKs plays a key role in triggering rapid desensitization. The GRK family consists of 7 isoforms that share a central catalytic domain with homology to other serine/threonine kinases. The catalytic domain is flanked by an amino-terminal RGS domain of 183 - 188 amino acids and a carboxyl-terminus of variable length. GRK1 and GRK7 are members of the rhodopsin kinase or visual GRK subfamily.
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #497007 |
Applications: | WB, IHC, ICC |
Reactivity: | Human |
Details: | Sheep IgG Polyclonal |
Applications: | WB, Simple Western |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #497018 |
Applications: | WB |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #SR2232 |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Applications: | WB, ELISA, MA, AP |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #10O6S3 |
Applications: | WB |
Applications: | WB, ELISA, MA, AP |
Applications: | WB |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB |
Applications: | AC |
Potent and selective GRK2/3 inhibitor
Chemical Name: | 3-[[[4-Methyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]methyl]amino]-N-[[2-(trifluoromethyl)phenyl]methyl]benzamide |
Purity: | ≥98% (HPLC) |