GRK3 Products
G protein-coupled receptor kinases (GRKs) are important modulators of G protein-coupled receptor (GPCR) signaling. Receptor phosphorylation by specific GRKs plays a key role in triggering rapid desensitization. The GRK family consists of 7 isoforms that share a central catalytic domain with homology to other serine/threonine kinases. The catalytic domain is flanked by an amino-terminal RGS domain of 183 - 188 amino acids and a carboxyl-terminus of variable length. GRK1 and GRK7 are members of the rhodopsin kinase or visual GRK subfamily.
9 results for "GRK3" in Products
9 results for "GRK3" in Products
GRK3 Products
G protein-coupled receptor kinases (GRKs) are important modulators of G protein-coupled receptor (GPCR) signaling. Receptor phosphorylation by specific GRKs plays a key role in triggering rapid desensitization. The GRK family consists of 7 isoforms that share a central catalytic domain with homology to other serine/threonine kinases. The catalytic domain is flanked by an amino-terminal RGS domain of 183 - 188 amino acids and a carboxyl-terminus of variable length. GRK1 and GRK7 are members of the rhodopsin kinase or visual GRK subfamily.
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #497007 |
| Applications: | WB, IHC, ICC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Simple Western |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #497018 |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #SR2232 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: GRK3 Antibody [NBP1-90008]](https://resources.bio-techne.com/images/products/GRK3-Antibody-Western-Blot-NBP1-90008-img0006.jpg "Western Blot: GRK3 Antibody [NBP1-90008]")
| Applications: | WB, ELISA, MA, AP |
![SDS-PAGE: Recombinant Human GRK3 GST (N-Term) Protein [H00000157-P01]](https://resources.bio-techne.com/images/products/Recombinant-Human-GRK3-Protein-SDS-Page-H00000157-P01-img0001.jpg "SDS-PAGE: Recombinant Human GRK3 GST (N-Term) Protein [H00000157-P01]")
| Applications: | WB, ELISA, MA, AP |
| Applications: | AC |
Potent and selective GRK2/3 inhibitor
| Chemical Name: | 3-[[[4-Methyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]methyl]amino]-N-[[2-(trifluoromethyl)phenyl]methyl]benzamide |
| Purity: | ≥98% (HPLC) |
