HGFR/c-MET Products
HGFR (Hepatocyte Growth Factor Receptor), also known as Met, is a receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. In the absence of ligand, HGFR forms noncovalent complexes with a variety of membrane proteins including CD44v6, CD151, EGFR, Fas, Integrin alpha 6 beta 4, Plexins B1, 2, 3, and MSPR/Ron.
Ligation of one complex component triggers activation of the other, followed by cooperative signaling effects. Formation of some of these heteromeric complexes is a requirement for epithelial cell morphogenesis and tumor cell invasion. Paracrine induction of epithelial cell scattering and branching tubulogenesis results from the stimulation of HGFR on undifferentiated epithelium by HGF released from neighboring mesenchymal cells.
Products:
414 results for "HGFR/c-MET" in Products
414 results for "HGFR/c-MET" in Products
HGFR/c-MET Products
HGFR (Hepatocyte Growth Factor Receptor), also known as Met, is a receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. In the absence of ligand, HGFR forms noncovalent complexes with a variety of membrane proteins including CD44v6, CD151, EGFR, Fas, Integrin alpha 6 beta 4, Plexins B1, 2, 3, and MSPR/Ron.
Ligation of one complex component triggers activation of the other, followed by cooperative signaling effects. Formation of some of these heteromeric complexes is a requirement for epithelial cell morphogenesis and tumor cell invasion. Paracrine induction of epithelial cell scattering and branching tubulogenesis results from the stimulation of HGFR on undifferentiated epithelium by HGF released from neighboring mesenchymal cells.
Products:
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #95106 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #527125 |
| Applications: | WB, KO |
(HEK293-expressed)
| Source: | HEK293 |
| Accession #: | P08581 (HGF R alpha ) & P08581 (HGF R beta ) |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #95308 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #95106 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #118624 |
| Applications: | WB |
| Reactivity: | Canine |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #118627 |
| Source: | NS0 |
| Accession #: | P16056 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #8 |
| Applications: | WB, ICC/IF, Flow, IP, CyTOF-ready, +1 More |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #95106 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #12.1 |
| Applications: | WB, ICC/IF, IP |
![Western Blot: HGFR/c-MET Antibody (12.1)BSA Free [NBP2-50169]](https://resources.bio-techne.com/images/products/HGF-R-c-MET-Antibody-12-1-Western-Blot-NBP2-50169-img0001.jpg "Western Blot: HGFR/c-MET Antibody (12.1)BSA Free [NBP2-50169]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG4 Monoclonal |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #A9A4-R |
| Applications: | IHC, WB |
| Source: | Sf 21 (baculovirus) |
| Accession #: | P16056 |
| Applications: | Bind |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #243 |
| Applications: | ELISA, Flow |
![Flow Cytometry: HGFR/c-MET Antibody (243) [NBP2-89295]](https://resources.bio-techne.com/images/products/HGFR-c-MET-Antibody-243-Flow-Cytometry-NBP2-89295-img0001.jpg "Flow Cytometry: HGFR/c-MET Antibody (243) [NBP2-89295]")
| Applications: | PAGE |
![SDS-PAGE: Recombinant Mouse HGFR/c-MET hIgG-His Protein [NBP2-77485]](https://resources.bio-techne.com/images/products/Recombinant-Mouse-HGFR-c-MET-hIgG-His-Protein-SDS-Page-NBP2-77485-img0001.jpg "SDS-PAGE: Recombinant Mouse HGFR/c-MET hIgG-His Protein [NBP2-77485]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG4 Monoclonal |
| Applications: | ELISA, Flow, Func |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: HGFR/c-MET Antibody [NBP2-55719]](https://resources.bio-techne.com/images/products/HGF-R-c-MET-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-55719-img0001.jpg "Immunocytochemistry/ Immunofluorescence: HGFR/c-MET Antibody [NBP2-55719]")
| Applications: | WB |
![Western Blot: HGFR/c-MET Overexpression Lysate [NBP2-11373]](https://resources.bio-techne.com/images/products/Met-c-Met-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-11373-img0001.jpg "Western Blot: HGFR/c-MET Overexpression Lysate [NBP2-11373]")