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HMGB1/HMG-1 Products

HMGB1 (high-mobility group box 1 protein), also known as HMG1 or Amphoterin, is an intracellular protein that is regulated by multiple posttranslational modifications including acetylation, phosphorylation, and methylation. HMGB1 is released upon cell necrosis, apoptosis, and pyroptosis. It acts as a multifunctional alarmin that stimulates inflammation upon sterile or infectious insult. Receptors for HMGB1 include TLR2, TLR4, TLR9, Syndecan-3, Siglec-10, Integrin alpha M beta 2, CXCR4, TIM-3, and RAGE. It is implicated in the pathogenesis of a broad range of diseases including atherosclerosis, sepsis, cancer, neurodegenerative diseases, and autoimmunity.

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240 results for "HMGB1/HMG-1" in Products

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240 results for "HMGB1/HMG-1" in Products

HMGB1/HMG-1 Products

HMGB1 (high-mobility group box 1 protein), also known as HMG1 or Amphoterin, is an intracellular protein that is regulated by multiple posttranslational modifications including acetylation, phosphorylation, and methylation. HMGB1 is released upon cell necrosis, apoptosis, and pyroptosis. It acts as a multifunctional alarmin that stimulates inflammation upon sterile or infectious insult. Receptors for HMGB1 include TLR2, TLR4, TLR9, Syndecan-3, Siglec-10, Integrin alpha M beta 2, CXCR4, TIM-3, and RAGE. It is implicated in the pathogenesis of a broad range of diseases including atherosclerosis, sepsis, cancer, neurodegenerative diseases, and autoimmunity.

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Applications: WB, IHC, ChIP, CyTOF-ready, ICC, ICFlow
Reactivity: Human
Applications: IHC, WB, ELISA, ICC/IF, Flow, B/N, KD, Simple Western
Reactivity: Human, Mouse, Rat, Canine, Bovine, +2 More
Applications: IHC, WB, ELISA, ICC/IF, Func, B/N, KD
Reactivity: Human, E. coli
Applications: IHC, WB, Flow, IP, CyTOF-ready, Func, Simple Western
Reactivity: Human, Mouse
Applications: WB, Simple Western, IHC
Reactivity: Human, Mouse, Rat
Applications: WB, KO
Reactivity: Human, Mouse
Applications: IHC, WB, ELISA, ICC/IF, MA
Reactivity: Human, Rat
Applications: ICFlow
Reactivity: Human
Applications: IHC, WB, ICC/IF, Flow, CyTOF-ready, Func, Simple Western
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow
Reactivity: Human, Mouse
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow, Simple Western
Reactivity: Human, Mouse
Applications: IHC, WB, ICC/IF, KO
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: ICFlow
Reactivity: Human
Applications: ICC
Reactivity: Human, Mouse
Applications: AC
Applications: WB, Simple Western
Reactivity: Human, Mouse
Applications: ICFlow
Reactivity: Human
Applications: WB, Flow, Simple Western
Reactivity: Human, Mouse
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
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