IL-1 beta/IL-1F2 Products
IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.
37 results for "IL-1 beta/IL-1F2" in Products
37 results for "IL-1 beta/IL-1F2" in Products
IL-1 beta/IL-1F2 Products
IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.
| Assay Range: | 15.6 - 1,000 pg/mL |
| Applications: | ELISA |
| Sensitivity: | 1 pg/mL |
| Applications: | ELISA |
| Assay Range: | 3.9 - 250 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Assay Range: | 3.91 - 250 pg/mL |
| Applications: | ELISA |
| Sensitivity: | 5 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma) |
| Sensitivity: | 0.063 pg/mL |
| Applications: | ELISA |
| Assay Range: | 0.125 - 8 pg/mL (Serum, EDTA Plasma, Heparin Plasma, Saliva) |
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #615417 |
| Applications: | WB, Simple Western, ICC |
| Sensitivity: | 0.55 pg/mL |
| Applications: | ELISA |
| Assay Range: | 1.4 - 1,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Source: | E. coli |
| Accession #: | Q28386 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #166926 |
| Applications: | WB |
| Reactivity: | Porcine |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Assay Range: | 7.81 - 500 pg/mL |
| Applications: | ELISA |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
| Source: | E. coli |
| Accession #: | NP_001033060 |
| Applications: | BA |
| Reactivity: | Rat |
| Details: | Mouse IgG1 Monoclonal Clone #38123 |
| Applications: | WB |
| Reactivity: | Feline |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
| Reactivity: | Equine |
| Details: | Mouse IgG1 Monoclonal Clone #608714 |
| Applications: | ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #8516 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #8516 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #8516 |
| Applications: | ICFlow |
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
