IL-27: Proteins and Enzymes
IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells. It signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12-induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.
Products:
7 results for "IL-27 Proteins and Enzymes" in Products
7 results for "IL-27 Proteins and Enzymes" in Products
IL-27: Proteins and Enzymes
IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells. It signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12-induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.
Products:
His-tag
| Source: | NS0 |
| Accession #: | Q14213.2 (EBI3) & AAM34498 (p28) |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | O35228 (EBI3) & Q8K3I6 (p28) |
| Applications: | BA |
| Source: | HEK293 |
| Accession #: | Q14213.2 & Q8NEV9.2 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | XP_005587614.1 (EBI-3) & XP_028697194.1 (IL-27a) |
| Applications: | BA |
Biotinylated
| Source: | NS0 |
| Accession #: | Q14213.2 |
| Applications: | BA |
| Applications: | AC |
| Applications: | AC |