Inositol Lipid Inhibitors: Small Molecules and Peptides
Inositol lipids are the structural basis of many second messenger molecules in eukaryotic cells. These include inositol monophosphate, inositol triphosphate (IP3) and inositol 1,4,5-trisphosphate (Ins (1,4,5)P3). Inositol lipid signaling pathways are regulated by phosphorylation.
11 results for "Inositol Lipid Inhibitors Small Molecules and Peptides" in Products
11 results for "Inositol Lipid Inhibitors Small Molecules and Peptides" in Products
Inositol Lipid Inhibitors: Small Molecules and Peptides
Inositol lipids are the structural basis of many second messenger molecules in eukaryotic cells. These include inositol monophosphate, inositol triphosphate (IP3) and inositol 1,4,5-trisphosphate (Ins (1,4,5)P3). Inositol lipid signaling pathways are regulated by phosphorylation.
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
| Chemical Name: | 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride |
| Purity: | ≥99% |
Potent, irreversible inhibitor of PI 3-kinase. Also inhibitor of PLK1
| Alternate Names: | SL-2052 |
| Chemical Name: | (1S,6bR,9aS,11R,11bR) 11-(Acetyloxy)-1,6b,7,8,9a,10,11,11b-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]indeno[4,5,-h]-2-h]-2-benzopyran-3,6,9-trione |
| Purity: | ≥98% (HPLC) |
Inhibitor of PI 3-kinase, mTOR and DNA-PK
| Chemical Name: | 3-[4-(4-Morpholinylpyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol hydrochloride |
| Purity: | ≥98% |
Class III PI 3-kinase inhibitor; also inhibits autophagy
| Alternate Names: | 3-MA |
| Chemical Name: | 3-Methyl-3H-purin-6-amine |
| Purity: | ≥99% (HPLC) |
PI 3-kinase inhibitor, more potent than LY 294002 (Cat. No. 1130)
| Chemical Name: | 2-(4-Morpholinyl)-8-(4-aminopheny)l-4H-1-benzopyran-4-one |
| Purity: | ≥98% |
Inositol monophosphatase inhibitor
| Chemical Name: | [1-(4-Hydroxyphenoxy)ethylidene]bisphosphonic acid |
Non-selective PI 3-kinase inhibitor
| Chemical Name: | 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one |
| Purity: | ≥98% (HPLC) |
Potent and selective PI 3-Kβ inhibitor
| Chemical Name: | (-)-2-[[(1R)-1-[7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid |
| Purity: | ≥98% |
Dual PI 3-kinase and PDPK1 (PDK1) inhibitor
| Chemical Name: | α,α,-Dimethyl-4-[2-methyl-8-[2-(3-pyridinyl)ethynyl]-1H-imidazo[4,5-c]quinolin-1-yl]-benzeneacetonitrile |
| Purity: | ≥98% |
Inhibitor of IP6K; also inhibits IP3K
| Chemical Name: | N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine |
| Purity: | ≥97% (HPLC) |
Potent and selective PI 3-kinase β inhibitor
| Chemical Name: | 7-Methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]-4H-pyrido[1,2-a]pyrimidin-4-one |
| Purity: | ≥98% (HPLC) |
