MAP3K8/Tpl2/COT: Proteins and Enzymes
MAP3K8, also called Tpl2 (tumor progression locus 2) or COT (Cancer Osaka Thyroid oncogene), is a cytosolic Ser/Thr kinase. MAP3K8 is one of the MAP kinase kinase (MAPKK) kinases that regulates the ERK1/ERK2 pathway in response to IL-1, facilitating IL-8 and MIP-1 beta production. MAP3K8 activates I kappa B kinases and induces the nuclear production of NF-kappa B.
3 results for "MAP3K8/Tpl2/COT Proteins and Enzymes" in Products
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MAP3K8/Tpl2/COT: Proteins and Enzymes
MAP3K8, also called Tpl2 (tumor progression locus 2) or COT (Cancer Osaka Thyroid oncogene), is a cytosolic Ser/Thr kinase. MAP3K8 is one of the MAP kinase kinase (MAPKK) kinases that regulates the ERK1/ERK2 pathway in response to IL-1, facilitating IL-8 and MIP-1 beta production. MAP3K8 activates I kappa B kinases and induces the nuclear production of NF-kappa B.
| Source: | Sf 9 (baculovirus) |
| Accession #: | NM_005204 |
| Applications: | BA |
| Applications: | AC |
| Applications: | AC |