MKK3 Products
Mitogen-activated protein kinase kinase 3 (MKK3), also known as MEK3, and the closely related MKK6 are activated by proinflammatory cytokines and environmental stresses. Activation occurs through phosphorylation by several upstream MAPK kinase kinases, including ASK1 and TAK1. Both MKK3 and MKK6 are dual specificity protein kinases, phosphorylating and activating the p38 MAP kinases at Thr and Tyr positions within the phosphoacceptor sequence Thr-Gly-Tyr.
9 results for "MKK3" in Products
9 results for "MKK3" in Products
MKK3 Products
Mitogen-activated protein kinase kinase 3 (MKK3), also known as MEK3, and the closely related MKK6 are activated by proinflammatory cytokines and environmental stresses. Activation occurs through phosphorylation by several upstream MAPK kinase kinases, including ASK1 and TAK1. Both MKK3 and MKK6 are dual specificity protein kinases, phosphorylating and activating the p38 MAP kinases at Thr and Tyr positions within the phosphoacceptor sequence Thr-Gly-Tyr.
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #275922 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #2E12D11 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +1 More |
![Western Blot: MKK3/MEK3 Antibody (2E12D11)BSA Free [NBP2-52508]](https://resources.bio-techne.com/images/products/MKK3-MEK3-Antibody-2E12D11-Western-Blot-NBP2-52508-img0007.jpg "Western Blot: MKK3/MEK3 Antibody (2E12D11)BSA Free [NBP2-52508]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #275909 |
| Applications: | WB, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1D10 |
| Applications: | IHC, WB, ELISA, IP |
![Western Blot: MKK3/MEK3 Antibody (1D10) [H00005606-M02]](https://resources.bio-techne.com/images/products/MKK3-MEK3-Antibody-1D10-Western-Blot-H00005606-M02-img0010.jpg "Western Blot: MKK3/MEK3 Antibody (1D10) [H00005606-M02]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #8U2X3 |
| Applications: | WB, ICC/IF |
![Western Blot: MKK3/MEK3 Antibody (8U2X3) [NBP3-16163]](https://resources.bio-techne.com/images/products/MKK3-MEK3-Antibody-8U2X3-Western-Blot-NBP3-16163-img0004.jpg "Western Blot: MKK3/MEK3 Antibody (8U2X3) [NBP3-16163]")
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human MKK3/MEK3 His Protein [NBP1-51069]](https://resources.bio-techne.com/images/products/Recombinant-Human-MKK3-MEK3-Protein-SDS-Page-NBP1-51069-img0001.jpg "SDS-PAGE: Recombinant Human MKK3/MEK3 His Protein [NBP1-51069]")
| Applications: | WB |
![Western Blot: MKK3/MEK3 Overexpression Lysate [NBL1-12848]](https://resources.bio-techne.com/images/products/MEK3-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-12848-img0002.jpg "Western Blot: MKK3/MEK3 Overexpression Lysate [NBL1-12848]")
Potent inhibitor of MEK1/2
| Alternate Names: | PD325901 |
| Chemical Name: | N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide |
| Purity: | ≥99% (HPLC) |
