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P-Selectin/CD62P Products

P-Selectin, also known as CD62P, GMP-140, PADGEM, and LECAM-3, is a transmembrane adhesion protein that is upregulated on activated platelets and vascular endothelial cells. It binds to hematopoietic cell PSGL-1/CD162 with highly clustered O-linked sialyl Lewis-x (sLex) tetrasaccharides and sulfated tyrosine, as well as to heparin sulfate, Versican, and CD42b/GPIb alpha. P-Selectin mediates the initial interaction of circulating leukocytes with activated endothelial cells that produce a characteristic ‘rolling’ of the leukocytes on the endothelium. It is therefore critical for leukocyte extravasation at sites of inflammation and leukocyte involvement in thrombus formation at sites of vascular injury.

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246 results for "P-Selectin/CD62P" in Products

P-Selectin/CD62P Products

P-Selectin, also known as CD62P, GMP-140, PADGEM, and LECAM-3, is a transmembrane adhesion protein that is upregulated on activated platelets and vascular endothelial cells. It binds to hematopoietic cell PSGL-1/CD162 with highly clustered O-linked sialyl Lewis-x (sLex) tetrasaccharides and sulfated tyrosine, as well as to heparin sulfate, Versican, and CD42b/GPIb alpha. P-Selectin mediates the initial interaction of circulating leukocytes with activated endothelial cells that produce a characteristic ‘rolling’ of the leukocytes on the endothelium. It is therefore critical for leukocyte extravasation at sites of inflammation and leukocyte involvement in thrombus formation at sites of vascular injury.

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Applications: IHC, AdBlk
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: WB, AdBlk
Reactivity: Human
Applications: WB
Reactivity: Mouse
Applications: WB
Reactivity: Human
Applications: WB, ICC/IF, Flow, IP, Func
Reactivity: Human, Primate
Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA
Reactivity: Mouse

Recombinant Monoclonal Antibody

Applications: ELISA
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC, Flow, IP
Reactivity: Human
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