PHLPP2 Products
PHLPP2 contains 21 LRR (leucine rich) repeats, 1 PH domain and 1 PP2C like domain. It is a protein phosphatase that specifically mediates dephosphorylation of AKT1 Ser 473, a protein that regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro and antiapoptotic genes. Dephosphorylation of Ser 473 of AKT1 triggers apoptosis and decrease cell proliferation. PHLPP2 also controls the phosphorylation of AKT3. It binds 2 manganese ions per subunit. There are 3 named isoforms produced by alternative splicing.
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43 results for "PHLPP2" in Products
43 results for "PHLPP2" in Products
PHLPP2 Products
PHLPP2 contains 21 LRR (leucine rich) repeats, 1 PH domain and 1 PP2C like domain. It is a protein phosphatase that specifically mediates dephosphorylation of AKT1 Ser 473, a protein that regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro and antiapoptotic genes. Dephosphorylation of Ser 473 of AKT1 triggers apoptosis and decrease cell proliferation. PHLPP2 also controls the phosphorylation of AKT3. It binds 2 manganese ions per subunit. There are 3 named isoforms produced by alternative splicing.
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Applications: WB, ELISA, ICC/IF
Reactivity:
Human
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: PHLPP2 AntibodyBSA Free [NBP2-81874]](https://resources.bio-techne.com/images/products/PHLPP2-Antibody-Western-Blot-NBP2-81874-img0001.jpg "Western Blot: PHLPP2 AntibodyBSA Free [NBP2-81874]")
Applications: WB, IP
Reactivity:
Human,
Mouse,
Rat
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: PHLPP2 Antibody [NB100-1812]](https://resources.bio-techne.com/images/products/PHLPP2-Antibody-Western-Blot-NB100-1812-img0002.jpg "Western Blot: PHLPP2 Antibody [NB100-1812]")
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: PHLPP2 Antibody [NBP2-19803]](https://resources.bio-techne.com/images/products/PHLPP2-Antibody-Western-Blot-NBP2-19803-img0001.jpg "Western Blot: PHLPP2 Antibody [NBP2-19803]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: PHLPP2 Antibody [NBP2-13757]](https://resources.bio-techne.com/images/products/PHLPP2-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-13757-img0004.jpg "Immunocytochemistry/ Immunofluorescence: PHLPP2 Antibody [NBP2-13757]")
Applications: WB, ELISA, ICC/IF
Reactivity:
Human,
Mouse,
Rat
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
Applications: WB, ELISA
Reactivity:
Human
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: PHLPP2 Antibody [NB100-61668]](https://resources.bio-techne.com/images/products/PHLPP2-Antibody-Western-Blot-NB100-61668-img0002.jpg "Western Blot: PHLPP2 Antibody [NB100-61668]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: PHLPP2 Antibody [NBP3-17909]](https://resources.bio-techne.com/images/products/PHLPP2-Antibody-Immunocytochemistry-Immunofluorescence-NBP3-17909-img0001.jpg "Immunocytochemistry/ Immunofluorescence: PHLPP2 Antibody [NBP3-17909]")
| Applications: | WB |
![Western Blot: PHLPP2 Overexpression Lysate [NBP2-07231]](https://resources.bio-techne.com/images/products/PHLPP2-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-07231-img0001.jpg "Western Blot: PHLPP2 Overexpression Lysate [NBP2-07231]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/Immunofluorescence: PHLPP2 Antibody [NBP3-21264] -](https://resources.bio-techne.com/images/products/nbp3-21264_rabbit-phlpp2-pab-4520231551145.jpg "Immunocytochemistry/Immunofluorescence: PHLPP2 Antibody [NBP3-21264] -")
Applications: WB, ELISA, ICC/IF
Reactivity:
Human
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
Applications: WB, ELISA, ICC/IF
Reactivity:
Human
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
Applications: WB, ELISA, ICC/IF
Reactivity:
Human
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
Applications: WB, ELISA, ICC/IF
Reactivity:
Human
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
Applications: WB, ELISA, ICC/IF
Reactivity:
Human
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Applications: | AC |
| Applications: | AC |
| Applications: | AC |
Applications: WB, ELISA, ICC/IF
Reactivity:
Human
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
Applications: WB, ELISA, ICC/IF
Reactivity:
Human
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
Applications: WB, ELISA, ICC/IF
Reactivity:
Human
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
Applications: WB, ELISA, ICC/IF
Reactivity:
Human
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
Applications: WB, ELISA, ICC/IF
Reactivity:
Human
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
Applications: WB, ELISA, ICC/IF
Reactivity:
Human
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
Applications: WB, ELISA, ICC/IF
Reactivity:
Human
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |