Protein Arginine Methyltransferase Inhibitors: Small Molecules and Peptides
12 results for "Protein Arginine Methyltransferase Inhibitors Small Molecules and Peptides" in Products
12 results for "Protein Arginine Methyltransferase Inhibitors Small Molecules and Peptides" in Products
Protein Arginine Methyltransferase Inhibitors: Small Molecules and Peptides
Potent and selective PRMT5 inhibitor
| Alternate Names: | EPZ015866,GSK 3203591 |
| Chemical Name: | 2-(Cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydropropyl]-4-pyridinecarboxamide dihydrochloride |
| Purity: | ≥97% (HPLC) |
Potent and selective PRMT 4 inhibitor
| Chemical Name: | N-Methyl-N-((2-(1-(2-(methylamino)ethyl)piperidin-4-yl)pyridin-4-yl)methyl)-3-phenoxybenzamide |
| Purity: | ≥98% (HPLC) |
Selective PRMT1 inhibitor
| Chemical Name: | 4,4'-(2,5-Furandiyl)bis-benzenecarboximidamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective type I PRMT inhibitor
| Chemical Name: | N1-Methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective PRMT5 inhibitor
| Chemical Name: | N-[(2S)-3-(3,4-Dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-6-(3-oxetanylamino)-4-pyrimidinecarboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective allosteric inhibitor of PRMT3
| Chemical Name: | 1-(Isoquinolin-6-yl)-3-[2-oxo-2-(pyrrolidin-1-yl)ethyl] urea |
| Purity: | ≥98% (HPLC) |
Allosteric inhibitor of PRMT3
| Chemical Name: | N-1,2,3-Benzothiadiazol-6-yl-N'-[2-oxo-2-(1-piperidinyl)ethyl]urea |
| Purity: | ≥99% (HPLC) |
Potent and selective PRMT6 allosteric inhibitor
| Chemical Name: | (R)-4-(5-Bromothiophene-2-carbonyl)-5-(3,5-dimethylphenyl)-7-methyl-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one |
| Purity: | ≥98% (HPLC) |
Potent and selective PRMT7 inhibitor
| Chemical Name: | N-(4-((((2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)butyl)-N-((4'-chloro-[1,1'-biphenyl]-3-yl)methyl)-3-methyl-3-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanamide |
| Purity: | ≥97% (HPLC) |
Negative control of SGC 707 (Cat. No. 5367)
| Chemical Name: | N-2-Naphthalenyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]urea |
| Purity: | ≥98% (HPLC) |
Negative control for SGC 6870 (Cat. No. 7182)
| Chemical Name: | (S)-4-(5-Bromothiophene-2-carbonyl)-5-(3,5-dimethylphenyl)-7-methyl-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one |
| Purity: | ≥98% (HPLC) |
Negative control for SGC 3027 (Cat. No. 6825)
| Chemical Name: | N-(4-((((3aS,4S,6R,6aR)-6-(6-Amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl)thio)butyl)-N-((4'-chloro-[1,1'-biphenyl]-3-yl)methyl)-3-methyl-3-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanamide |
| Purity: | ≥98% (HPLC) |
