RIPK3/RIP3: Small Molecules and Peptides
RIPK3 (), also known as RIP3, is a 518 amino acid (aa), 60 kDa phosphoprotein that contains an N-terminal protein kinase domain and a C-terminal interaction motif with which it binds RIPK1. It converts cell response to TNF-alpha from apoptosis (RIPK1 via Fas) to programmed necrosis (RIPK1/RIPK3) by inducing reactive oxygen species production. Al...
3 results for "RIPK3/RIP3 Small Molecules and Peptides" in Products
3 results for "RIPK3/RIP3 Small Molecules and Peptides" in Products
RIPK3/RIP3: Small Molecules and Peptides
RIPK3 (), also known as RIP3, is a 518 amino acid (aa), 60 kDa phosphoprotein that contains an N-terminal protein kinase domain and a C-terminal interaction motif with which it binds RIPK1. It converts cell response to TNF-alpha from apoptosis (RIPK1 via Fas) to programmed necrosis (RIPK1/RIPK3) by inducing reactive oxygen species production. Al...
Potent and selective RIPK3 inhibitor; also blocks activation of necroptosis
| Chemical Name: | 3-(3-Hydroxyphenyl)-1-methyl-7-[[3-(4-methyl-1-piperazinyl)phenyl]amino]-1,6-naphthyridin-2(1H)-one dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective RIP3 kinase inhibitor
| Chemical Name: | N-5-Benzothiazolyl-6-[(1-methylethyl)sulfonyl]-4-quinolinamine |
| Purity: | ≥98% (HPLC) |
Necroptosis inhibitor; also inhibits pyroptosis
| Chemical Name: | (2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide |
| Purity: | ≥98% (HPLC) |
