S1P2/EDG-5 Products
EDG molecules are G protein-coupled receptors that bind plasma lysophospholipids. The EDG family consists of two subfamilies; the S1P (sphingosine-1-phosphate) subfamily consisting of EDG-1, 3, 5, 6, and 8, and the LPA (lysophosphatidic acid) subfamily that contains EDG-2, 4 and 7. Each receptor is the product of a distinct gene. The S1P family regulates essential cellular processes such as proliferation, migration, cytoskeletal organization, and differentiation.
14 results for "S1P2/EDG-5" in Products
14 results for "S1P2/EDG-5" in Products
S1P2/EDG-5 Products
EDG molecules are G protein-coupled receptors that bind plasma lysophospholipids. The EDG family consists of two subfamilies; the S1P (sphingosine-1-phosphate) subfamily consisting of EDG-1, 3, 5, 6, and 8, and the LPA (lysophosphatidic acid) subfamily that contains EDG-2, 4 and 7. Each receptor is the product of a distinct gene. The S1P family regulates essential cellular processes such as proliferation, migration, cytoskeletal organization, and differentiation.
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: S1P2/EDG-5/S1PR2 Antibody [NBP2-26691]](https://resources.bio-techne.com/images/products/S1P2-EDG-5-S1PR2-Antibody-Western-Blot-NBP2-26691-img0002.jpg "Western Blot: S1P2/EDG-5/S1PR2 Antibody [NBP2-26691]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | IHC, ELISA, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: S1P2/EDG-5/S1PR2 Antibody [NBP3-14465]](https://resources.bio-techne.com/images/products/S1P2-EDG-5-S1PR2-Antibody-Immunocytochemistry-Immunofluorescence-NBP3-14465-img0001.jpg "Immunocytochemistry/ Immunofluorescence: S1P2/EDG-5/S1PR2 Antibody [NBP3-14465]")
| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | WB |
![Western Blot: S1P2/EDG-5/S1PR2 Antibody [NBP3-10068]](https://resources.bio-techne.com/images/products/S1P2-EDG-5-S1PR2-Antibody-Western-Blot-NBP3-10068-img0001.jpg "Western Blot: S1P2/EDG-5/S1PR2 Antibody [NBP3-10068]")
| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | IHC, ELISA, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: S1P2/EDG-5/S1PR2 Antibody [NBP3-14466]](https://resources.bio-techne.com/images/products/S1P2-EDG-5-S1PR2-Antibody-Immunocytochemistry-Immunofluorescence-NBP3-14466-img0001.jpg "Immunocytochemistry/ Immunofluorescence: S1P2/EDG-5/S1PR2 Antibody [NBP3-14466]")
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: S1P2/EDG-5/S1PR2 Antibody [NBP1-68854]](https://resources.bio-techne.com/images/products/S1PR2-Antibody-Western-Blot-NBP1-68854-img0002.jpg "Western Blot: S1P2/EDG-5/S1PR2 Antibody [NBP1-68854]")
| Applications: | AC |
S1P2 receptor antagonist
| Chemical Name: | 1-[1,3-Dimethyl-4-(2-methylethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]-4-(3,5-dichloro-4-pyridinyl)-semicarbazide |
| Purity: | ≥98% (HPLC) |
Endogenous agonist at S1P1-5
| Chemical Name: | (E)-D-erythro-2-amino-1-(dihydrogenphosphate)-4-octadecene-1,3-diol |
| Purity: | ≥98% (HPLC) |
Selective S1P2 allosteric agonist
| Chemical Name: | 1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-1,6-dihydro-6-oxo-3-pyridinecarbonitrile |
| Purity: | ≥99% (HPLC) |
Potent S1P receptor agonist; also immunosuppressant
| Alternate Names: | Fingolimod,Gilenya |
| Chemical Name: | 2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride |
| Purity: | ≥99% (HPLC) |
