TCF7/TCF1 Products
TCF7 (Transcription factor 7; also T cell factor 1/TCF1) is a 25 - 50 kDa member of the lymphoid enhancer binding factor family of proteins with 16 isoforms. It is expressed in thymocytes and mature T cells, and serves multiple purposes. In resting cells, TCF family members are transcriptional repressors, and are 25 - 32 kDa in size. Following activation, large TCF7 isoforms predominate (42 - 50 kDa), and serve a transcriptional activator function. Human TCF7 is 384 amino acids (aa) in length. This is likely an activating isoform that contains a beta-Catenin binding domain (aa 1 - 59), a DNA-binding HMG-box (aa 269 - 337), and an NLS (aa 344 - 348). The use of an alternate start site at Met116 seems to characterize repressor isoforms.
45 results for "TCF7/TCF1" in Products
45 results for "TCF7/TCF1" in Products
TCF7/TCF1 Products
TCF7 (Transcription factor 7; also T cell factor 1/TCF1) is a 25 - 50 kDa member of the lymphoid enhancer binding factor family of proteins with 16 isoforms. It is expressed in thymocytes and mature T cells, and serves multiple purposes. In resting cells, TCF family members are transcriptional repressors, and are 25 - 32 kDa in size. Following activation, large TCF7 isoforms predominate (42 - 50 kDa), and serve a transcriptional activator function. Human TCF7 is 384 amino acids (aa) in length. This is likely an activating isoform that contains a beta-Catenin binding domain (aa 1 - 59), a DNA-binding HMG-box (aa 269 - 337), and an NLS (aa 344 - 348). The use of an alternate start site at Met116 seems to characterize repressor isoforms.
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #812145 |
Applications: | ICFlow |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #812145 |
Applications: | WB, CyTOF-ready, ICFlow |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #812145 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #1D2 |
Applications: | IHC, WB, ELISA, ICC/IF, B/N |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, IHC, ICC |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #812145 |
Applications: | ICFlow |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #812145 |
Applications: | ICFlow |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #812145 |
Applications: | ICFlow |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #812145 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG2a Kappa Monoclonal Clone #2E9 |
Applications: | IHC, WB, ELISA, B/N |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #812145 |
Applications: | ICFlow |
Applications: | WB, ELISA, MA, AP |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #1B3 |
Applications: | WB, ELISA |
Applications: | WB |
Applications: | WB, ELISA, MA, AP, PAGE |
Reactivity: | Mouse |
Details: | Rabbit Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | ICC/IF |
Applications: | AC |
Applications: | AC |
Reactivity: | Mouse |
Details: | Rat IgG2B Monoclonal Clone #812145 |
Applications: | WB, Flow, CyTOF-ready |
Reactivity: | Mouse |
Details: | Rat IgG2B Monoclonal Clone #812145 |
Applications: | WB, Flow, CyTOF-ready |
Reactivity: | Mouse |
Details: | Rat IgG2B Monoclonal Clone #812145 |
Applications: | WB, Flow, CyTOF-ready |
Reactivity: | Mouse |
Details: | Rat IgG2B Monoclonal Clone #812145 |
Applications: | WB, Flow, CyTOF-ready |
Reactivity: | Mouse |
Details: | Rat IgG2B Monoclonal Clone #812145 |
Applications: | WB, Flow, CyTOF-ready |