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TIMP-2 Products

TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.

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66 results for "TIMP-2" in Products

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66 results for "TIMP-2" in Products

TIMP-2 Products

TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.

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Applications: IHC
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More

Recombinant Monoclonal Antibody

Applications: WB, IHC, Dual ISH-IHC, KO, Neut
Reactivity: Human, Mouse
Applications: IHC, WB, ICC/IF
Reactivity: Human, Mouse
Applications: IHC, WB, ICC/IF, Flow
Reactivity: Human, Mouse, Rat, Canine, Monkey
Applications: IHC, WB, ELISA
Reactivity: Human, Mouse, Zebrafish, Porcine, Rabbit, +1 More
Applications: WB
Reactivity: Human, Mouse, Rat, Monkey

Recombinant Monoclonal Antibody

Applications: IHC, WB, ICC/IF, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More
Applications: IHC, WB, ICC/IF, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More
Applications: IHC, WB, ICC/IF, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More
Applications: IHC, WB, ICC/IF, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More
Applications: IHC, WB, ICC/IF, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More
Applications: IHC, WB, ICC/IF, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More
Applications: IHC, WB, ICC/IF, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More
Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat, Canine, Monkey
Applications: IHC, WB, ICC/IF, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More
Applications: IHC, WB, ICC/IF, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More
Applications: IHC, WB, ICC/IF, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More
Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat, Canine, Monkey
Applications: IHC, WB, ICC/IF, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More
Applications: IHC, WB, ICC/IF, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More
Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat, Canine, Monkey
Applications: IHC, WB, ICC/IF, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More
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