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TIMP-2 Products

TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.

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145 results for "TIMP-2" in Products

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145 results for "TIMP-2" in Products

TIMP-2 Products

TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.

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Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC, ELISA, MA
Reactivity: Human
Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC, ELISA, MA
Reactivity: Human
Applications: IHC
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More

Recombinant Monoclonal Antibody

Applications: IHC, ELISA, MA
Reactivity: Human
Applications: Simple Plex

Build your own multi-plex biomarker immunoassay panel for Ella™. Highly precise and reproducible. Choose from more than 250 fully validated target analytes.

Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies

Applications: WB, IHC, Dual ISH-IHC, KO, Neut
Reactivity: Human, Mouse
Applications: Simple Plex

Simple Plex Human TIMP-2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: WB, IHC
Reactivity: Human

For the measurement of TIMP-1, TIMP-2, and TIMP-4. Earn double rewards for reviews

Applications: IHC, WB, ICC/IF, Flow
Reactivity: Human, Mouse, Rat, Canine, Monkey
Applications: WB
Applications: WB, IHC, KO
Reactivity: Human

Recombinant Monoclonal Antibody.

Contains 4 membranes-2 spotted in duplicate with antibodies against 35 different proteases and 2 spotted in duplicate with antibodies against 32 different protease inhibitors

Applications: KO
Reactivity: Human
Applications: WB
Reactivity: Human
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