TIMP-2 Products
TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.
227 results for "TIMP-2" in Products
227 results for "TIMP-2" in Products
TIMP-2 Products
TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #TIMP2/8193R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat, Bovine, Rabbit, +2 More |
Details: | Rabbit IgG Monoclonal Clone #TIMP2/2488R |
Applications: | IHC |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #TIMP2/2044 |
Applications: | IHC, ELISA, MA |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #TIMP2/8193R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat, Bovine, Rabbit, +2 More |
Details: | Rabbit IgG Monoclonal Clone #TIMP2/2488R |
Applications: | IHC |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #TIMP2/2044 |
Applications: | IHC, ELISA, MA |
Sensitivity: | 0.064 ng/mL |
Applications: | ELISA |
Assay Range: | 0.156 - 10 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Urine) |
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Applications: | Simple Plex |
Reactivity: | Human, Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, IHC, Dual ISH-IHC, KO, Neut |
Simple Plex Human TIMP-2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
For the measurement of TIMP-1, TIMP-2, and TIMP-4. Earn double rewards for reviews
Assay Range: | 31.2 - 2,000 pg/mL |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #89025 |
Applications: | WB, IHC |
Source: | CHO |
Accession #: | P16035 |
Applications: | InhibAct |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Goat IgG Monoclonal Clone #40019A |
Applications: | WB, IHC, KO |
Source: | NS0 |
Accession #: | NP_035724 |
Applications: | EnzAct |
Contains 4 membranes-2 spotted in duplicate with antibodies against 35 different proteases and 2 spotted in duplicate with antibodies against 32 different protease inhibitors
Reactivity: | Human, Mouse, Rat, Canine, Monkey |
Details: | Mouse IgG1 Monoclonal Clone #OTI1A6 |
Applications: | IHC, WB, ICC/IF, Flow |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #127711 |
Applications: | KO |
Source: | CHO |
Applications: | WB |
For use with catalog number DTM200
Applications: | ELISA, Ctrl |
Assay Range: | 7.81 - 500 pg/mL |
Applications: | ELISA |
Control for use with Human and Non-Human Primate TIMP-2 Simple Plex Assay Cartridge Kit
Applications: | Ctrl, Simple Plex |
Reactivity: | Human, Mouse |
Details: | Mouse IgG2a Kappa Monoclonal Clone #F27 P3 A4 |
Applications: | IHC, WB, ICC/IF |