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VEGF-C Products

Vascular endothelial growth factor C (VEGF-C) is a homodimeric ligand of VEGF R3/Flt-4 and is synthesized with N- and C-terminal propeptides. Fully processed VEGF-C containing only the VEGF homology domain can additionally bind and activate VEGF R2/KDR/Flk-1. VEGF-C interactions with VEGF R3 are critical for lymphangiogenesis. Both the ligand and receptor are usually co-expressed at sites of lymphatic vessel sprouting, in the embryo, and in various pathological conditions. Over-expression of VEGF-C in tumor cells induces tumoral lymphatic hyperplasia, neoangiogenesis, and vessel sprouting, resulting in enhanced lymph flow and metastasis to regional lymph nodes.

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163 results for "VEGF-C" in Products

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163 results for "VEGF-C" in Products

VEGF-C Products

Vascular endothelial growth factor C (VEGF-C) is a homodimeric ligand of VEGF R3/Flt-4 and is synthesized with N- and C-terminal propeptides. Fully processed VEGF-C containing only the VEGF homology domain can additionally bind and activate VEGF R2/KDR/Flk-1. VEGF-C interactions with VEGF R3 are critical for lymphangiogenesis. Both the ligand and receptor are usually co-expressed at sites of lymphatic vessel sprouting, in the embryo, and in various pathological conditions. Over-expression of VEGF-C in tumor cells induces tumoral lymphatic hyperplasia, neoangiogenesis, and vessel sprouting, resulting in enhanced lymph flow and metastasis to regional lymph nodes.

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Applications: WB, ELISA, IHC
Reactivity: Human
Applications: BA, Bind
Applications: IHC, WB, ICC/IF
Reactivity: Human, Mouse, Rat, Fish - Danio rerio (Zebrafish)
Applications: IHC, WB, ICC/IF, ELISA
Reactivity: Human, Rat
Applications: WB
Reactivity: Human
Applications: IHC, WB
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ICC/IF
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC, WB, KD
Reactivity: Human, Mouse, Rat, Bovine
Applications: IHC, WB
Reactivity: Human
Applications: IHC, WB
Reactivity: Human, Rat
Applications: WB, ELISA
Reactivity: Human, Rat
Applications: ELISA
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: WB, ELISA
Reactivity: Human, Rat
Applications: WB
Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC, WB
Reactivity: Human, Mouse, Rat
Applications: IHC, WB
Reactivity: Human, Mouse, Rat
Applications: IHC, WB
Reactivity: Human, Mouse, Rat
Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Rat
Applications: IHC, WB
Reactivity: Human, Rat
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