Human Integrin  alpha8 APC-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB6194A

R&D Systems, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 481709

View all Integrin alpha 8 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human Integrin alpha8
Glu610-Leu800
Accession # P53708

Specificity

Detects human Integrin alpha8 in direct ELISAs and Western blots.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for Human Integrin  alpha8 APC-conjugated Antibody

Detection of Integrin a8 antibody in H4 Human Cell Line antibody by Flow Cytometry.

Detection of Integrin alpha8 in H4 Human Cell Line by Flow Cytometry.

H4 human neuroglioma cell line was stained with Mouse Anti-Human Integrin a8 APC-conjugated Monoclonal Antibody (Catalog # FAB6194A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Human Integrin  alpha8 APC-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: H4 human neuroglioma cell line

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: Integrin alpha 8

Integrin alpha8 is a 170-200 kDa member of the Integrin family of adhesion molecules. It forms an exclusive noncovalent heterodimer with Integrin beta1. Integrin alpha8/ beta1 promotes both cell adhesion and survival, and is known to bind to fibronectin, LAP-TGF beta1 and Nephronectin. It is principally expressed in smooth muscle cells.  Human alpha8 is a 1025 amino acid (aa) type I transmembrane glycoprotein. It contains a 974 aa extracellular domain (ECD) (aa 39-1012) and a 30 aa cytoplasmic domain. In the ECD, human alpha8 shares 90% aa sequence identity with mouse alpha8 protein.

Alternate Names

ITGA8

Entrez Gene IDs

8516 (Human); 241226 (Mouse); 84381 (Rat)

Gene Symbol

ITGA8

UniProt

P53708

Additional Integrin alpha 8 Products

Product Documents for Human Integrin  alpha8 APC-conjugated Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human Integrin  alpha8 APC-conjugated Antibody

For research use only

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