H4 human neuroglioma cell line was stained with Mouse Anti-Human Integrin a8 PE-conjugated Monoclonal Antibody (Catalog # FAB6194P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Human Integrin alpha8 PE-conjugated Antibody

Application

Recommended Usage

Flow Cytometry

10 µL/10⁶ cells
Sample: H4 human neuroglioma cell line

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: Integrin alpha 8

Integrin alpha8 is a 170-200 kDa member of the Integrin family of adhesion molecules. It forms an exclusive noncovalent heterodimer with Integrin beta1. Integrin alpha8/ beta1 promotes both cell adhesion and survival, and is known to bind to fibronectin, LAP-TGF beta1 and Nephronectin. It is principally expressed in smooth muscle cells. Human alpha8 is a 1025 amino acid (aa) type I transmembrane glycoprotein. It contains a 974 aa extracellular domain (ECD) (aa 39-1012) and a 30 aa cytoplasmic domain. In the ECD, human alpha8 shares 90% aa sequence identity with mouse alpha8 protein.

Alternate Names

ITGA8

Entrez Gene IDs

8516 (Human); 241226 (Mouse); 84381 (Rat)

Gene Symbol

ITGA8

UniProt

P53708

Additional Integrin alpha 8 Products

Product Documents for Human Integrin alpha8 PE-conjugated Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Human Integrin alpha8 PE-conjugated Antibody

For research use only

Citations
Reviews

Spectra Viewer
Flow Cytometry

Human Integrin alpha8 PE-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB6194P

Key Product Details

Species Reactivity

Validated:

Cited:

Applications

Validated:

Cited:

Label

Antibody Source

View all Integrin alpha 8 Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Scientific Data Images for Human Integrin alpha8 PE-conjugated Antibody

Detection of Integrin alpha8 in H4 Human Cell Line by Flow Cytometry.