IGF-II R/IGF2R Antibody (MEM-238) [CoraFluor™ 1]
Novus Biologicals, part of Bio-Techne | Catalog # NB500-464CL1
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Validated:
Human, Primate
Applications
CyTOF-ready, Flow Cytometry, Immunoprecipitation, Western Blot
Label
CoraFluor 1
Antibody Source
Monoclonal Mouse IgG1 Clone # MEM-238
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for IGF-II R/IGF2R Antibody (MEM-238) [CoraFluor™ 1]
Immunogen
Recombinant Vaccinia virus encoding CD222.
Epitope
Recognizes an epitope between domains 2 and 5.
Specificity
The antibody MEM-238 recognizes an epitope between domains 2 and 5 of CD222 (IGF2 receptor), a ubiquitously expressed 250 kDa multifunctional type I transmembrane protein. The majority of CD222 is found in the late endosomal/prelysosomal ompartment, 5-10% in the plasma membrane and the truncated (220 kDa) form of CD222 is present in human and bovine serum.
Marker
Late Endosome Marker
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Applications for IGF-II R/IGF2R Antibody (MEM-238) [CoraFluor™ 1]
Application
Recommended Usage
CyTOF-ready
Optimal dilutions of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Immunoprecipitation
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
PBS
Preservative
No Preservative
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark. Do not freeze.
Background: IGF-II R/IGF2R
Long Name
Insulin-like Growth Factor II Receptor
Alternate Names
CD222, CIMPR, IGF-IIR, IGF2R, IGFIIR, M6P-R, MPRI
Gene Symbol
IGF2R
Additional IGF-II R/IGF2R Products
Product Documents for IGF-II R/IGF2R Antibody (MEM-238) [CoraFluor™ 1]
Product Specific Notices for IGF-II R/IGF2R Antibody (MEM-238) [CoraFluor™ 1]
CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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