IGF-II R/IGF2R Products
IGF-II R/IGF2R is a type I transmembrane glycoprotein that contains a 2,264 amino acid (aa) extracellular region, a 23 aa transmembrane segment segment and a 124 aa cytoplasmic tail. IGF2R regulates many diverse biological functions that range from intracellular trafficking to the internalization of extracellular factors and modulation of cellular responses. It delivers newly synthesized M6P-tagged lysosomal enzymes from the trans-golgi network to endosomes, and facilitates the clearance of extracellular lysosomal and matrix degrading enzymes by internalization into clathrin-coated vesicles and delivery into endosomes. With respect to IGF2 biology, It would appear that IGF2R is principally a regulator of local IGF2 levels, targeting IGF2 for destruction in lysosomes.
Products:
70 results for "IGF-II R/IGF2R" in Products
70 results for "IGF-II R/IGF2R" in Products
IGF-II R/IGF2R Products
IGF-II R/IGF2R is a type I transmembrane glycoprotein that contains a 2,264 amino acid (aa) extracellular region, a 23 aa transmembrane segment segment and a 124 aa cytoplasmic tail. IGF2R regulates many diverse biological functions that range from intracellular trafficking to the internalization of extracellular factors and modulation of cellular responses. It delivers newly synthesized M6P-tagged lysosomal enzymes from the trans-golgi network to endosomes, and facilitates the clearance of extracellular lysosomal and matrix degrading enzymes by internalization into clathrin-coated vesicles and delivery into endosomes. With respect to IGF2 biology, It would appear that IGF2R is principally a regulator of local IGF2 levels, targeting IGF2 for destruction in lysosomes.
Products:
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC, Block, CyTOF-ready, +1 More |
| Reactivity: | Human, Mouse, Rat, Bovine, Primate |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #2G11 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
![Immunocytochemistry/ Immunofluorescence: IGF-II R/IGF2R Antibody (2G11) - BSA Free [NB300-514]](https://resources.bio-techne.com/images/products/IGF-II-R-IGF2R-Antibody-2G11-Immunocytochemistry-Immunofluorescence-NB300-514-img0014.jpg "Immunocytochemistry/ Immunofluorescence: IGF-II R/IGF2R Antibody (2G11) - BSA Free [NB300-514]")
| Source: | CHO |
| Accession #: | P11717.3 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | P11717.2 |
| Applications: | Bind |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #372604 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #372616 |
| Assay Range: | 156 - 10,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #MEM-238 |
| Applications: | WB, Flow, IP, CyTOF-ready |
![Western Blot: IGF-II R/IGF2R Antibody (MEM-238)BSA Free [NB500-464]](https://resources.bio-techne.com/images/products/IGF-II-R-Mannose-6-Phosphate-Receptor-Cation-independent-Antibody-MEM-238-Western-Blot-NB500-464-img0001.jpg "Western Blot: IGF-II R/IGF2R Antibody (MEM-238)BSA Free [NB500-464]")
| Reactivity: | Human, Mouse, Bovine, Primate, Plant |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF, DB, NULL |
![Western Blot: IGF-II R/IGF2R Antibody [NB100-74387]](https://resources.bio-techne.com/images/products/IGF-II-R-Mannose-6-Phosphate-Receptor-Cation-independent-Antibody-Western-Blot-NB100-74387-img0012.jpg "Western Blot: IGF-II R/IGF2R Antibody [NB100-74387]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: IGF-II R/IGF2R Antibody [NBP1-84598]](https://resources.bio-techne.com/images/products/IGF-II-R-Mannose-6-Phosphate-Receptor-Cation-independent-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-84598-img0004.jpg "Immunocytochemistry/ Immunofluorescence: IGF-II R/IGF2R Antibody [NBP1-84598]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #4J4A3 |
| Applications: | WB, ICC/IF |
![Western Blot: IGF-II R/IGF2R Antibody (4J4A3) [NBP3-16270]](https://resources.bio-techne.com/images/products/IGF-II-R-IGF2R-Antibody-4J4A3-Western-Blot-NBP3-16270-img0003.jpg "Western Blot: IGF-II R/IGF2R Antibody (4J4A3) [NBP3-16270]")
Clone MEM-240 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #MEM-240 |
| Applications: | WB, Flow, IP |
![Flow Cytometry: IGF-II R/IGF2R Antibody (MEM-240) - BSA Free [NBP3-09145]](https://resources.bio-techne.com/images/products/IGF-II-R-IGF2R-Antibody-MEM-240-Flow-Cytometry-NBP3-09145-img0003.jpg "Flow Cytometry: IGF-II R/IGF2R Antibody (MEM-240) - BSA Free [NBP3-09145]")
| Applications: | AC |
| Reactivity: | Human, Mouse, Rat, Bovine, Primate |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #2G11 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
| Reactivity: | Human, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #MEM-238 |
| Applications: | WB, Flow, IP, CyTOF-ready |
| Reactivity: | Human, Mouse, Rat, Bovine, Primate |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #2G11 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
| Reactivity: | Human, Mouse, Rat, Bovine, Primate |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #2G11 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
| Reactivity: | Human, Mouse, Rat, Bovine, Primate |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #2G11 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
| Reactivity: | Human, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #MEM-238 |
| Applications: | WB, Flow, IP, CyTOF-ready |
| Reactivity: | Human, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #MEM-238 |
| Applications: | WB, Flow, IP, CyTOF-ready |
| Reactivity: | Human, Mouse, Rat, Bovine, Primate |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #2G11 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
| Reactivity: | Human, Mouse, Rat, Bovine, Primate |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #2G11 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
| Reactivity: | Human, Mouse, Rat, Bovine, Primate |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #2G11 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |