5-HT4 Products
5HT4R, also known as HTR4, is an approximately 45 kDa multipass serotonin receptor that is expressed in the brain, gastrointestinal tract, bladder, vascular endothelial cells, atrium, kidney, and adrenal gland. It is involved in the regulation of learning, memory, anxiety, smooth muscle contraction, and adrenal corticosteroid secretion. Alternate splicing of human 5HT4R generates multiple isoforms with either a 14 aa insertion in the second extracellular loop or a deletion or various substitutions in the C-terminal cytoplasmic region. Different isoforms show tissue specific expression patterns or increased activity in the absence of ligand. Human 5HT4R shares 94% and 88% aa sequence identity with mouse and rat 5HT4R, respectively.
125 results for "5-HT4" in Products
125 results for "5-HT4" in Products
5-HT4 Products
5HT4R, also known as HTR4, is an approximately 45 kDa multipass serotonin receptor that is expressed in the brain, gastrointestinal tract, bladder, vascular endothelial cells, atrium, kidney, and adrenal gland. It is involved in the regulation of learning, memory, anxiety, smooth muscle contraction, and adrenal corticosteroid secretion. Alternate splicing of human 5HT4R generates multiple isoforms with either a 14 aa insertion in the second extracellular loop or a deletion or various substitutions in the C-terminal cytoplasmic region. Different isoforms show tissue specific expression patterns or increased activity in the absence of ligand. Human 5HT4R shares 94% and 88% aa sequence identity with mouse and rat 5HT4R, respectively.
Endogenous 5-HT receptor agonist
| Alternate Names: | 5-Hydroxytryptamine,5-HT |
| Chemical Name: | 3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride |
| Purity: | ≥98% (HPLC) |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: 5-HT4 AntibodyBSA Free [NBP1-78403]](https://resources.bio-techne.com/images/products/5-HT4-Antibody-Western-Blot-NBP1-78403-img0003.jpg "Western Blot: 5-HT4 AntibodyBSA Free [NBP1-78403]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #631769 |
| Applications: | Flow, IHC |
Potent and selective 5-HT4 antagonist
| Chemical Name: | 1-methyl-1H-indole-3-carboxylic acid, [1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]methyl ester |
| Purity: | ≥98% (HPLC) |
α partial agonist; also D2-like partial agonist and 5-HT antagonist
| Chemical Name: | 9,10-Dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotaman-3',6',18-trione mesylate |
| Purity: | ≥98% (HPLC) |
5-HT4 antagonist
| Chemical Name: | 1-[4-Amino-5-chloro-2-(3,5-dimethoxyphenyl)methyloxy]-3-[1-[2-methylsulphonylamino]ethyl]piperidin-4-yl]propan-1-one hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent 5-HT4 agonist
| Chemical Name: | 2,3-Dihydro-N-[(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-3-(1-methylethyl)-2-oxo-1H-benzimidazole-1-carboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective 5-HT4 antagonist; active in vivo
| Chemical Name: | 5-Fluoro-2-methoxy-[1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]-1H-indole-3-methylcarboxylate sulfamate |
| Purity: | ≥97% (HPLC) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: 5-HT4 Antibody [NBP2-99479]](https://resources.bio-techne.com/images/products/5-HT4-Antibody-Western-Blot-NBP2-99479-img0003.jpg "Western Blot: 5-HT4 Antibody [NBP2-99479]")
5-HT4 agonist; stimulates intestinal ACh release
| Alternate Names: | R 51619 |
| Chemical Name: | (±)-4-Amino-5-chloro-N-[1-[(3R*,4S*)-3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide |
| Purity: | ≥99% (HPLC) |
5-HT4 antagonist
| Chemical Name: | 3-(Piperidin-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride |
Highly potent 5-HT3 antagonist; also 5-HT4 agonist
| Chemical Name: | (±)-4-Amino-N-1-azabicyclo[2.2.2]oct-3-yl-5-chloro-2-methoxybenzamide hydrochloride |
| Purity: | ≥99% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #631769 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #631769 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #631769 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #631769 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #631769 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #631769 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #631769 |
| Applications: | Flow |
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human, Monkey |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: 5-HT4 Antibody - BSA Free [NLS655]](https://resources.bio-techne.com/images/products/5-HT4-Antibody-Immunohistochemistry-Paraffin-NLS655-img0005.jpg "Immunohistochemistry-Paraffin: 5-HT4 Antibody - BSA Free [NLS655]")
| Applications: | AC |
| Applications: | ELISA |
