Activin RIB/ALK-4 Products
Receptors for the TGF-beta superfamily comprise two groups, the type I and the type II serine/threonine kinases. These kinases are type I transmembrane proteins, and the two subgroups are distinguished by the presence of a glycine/serine-rich juxta-membrane domain found in the type I receptors. Either a type I or type II receptor may initially bind ligand, followed by recruitment of its alternate-type receptor counterpart to generate a heteromeric signaling complex. Type I receptors are referred to as the Activin Receptor-like Kinases (ALKs), while the type II receptors are named for the ligands they bind.
59 results for "Activin RIB/ALK-4" in Products
59 results for "Activin RIB/ALK-4" in Products
Activin RIB/ALK-4 Products
Receptors for the TGF-beta superfamily comprise two groups, the type I and the type II serine/threonine kinases. These kinases are type I transmembrane proteins, and the two subgroups are distinguished by the presence of a glycine/serine-rich juxta-membrane domain found in the type I receptors. Either a type I or type II receptor may initially bind ligand, followed by recruitment of its alternate-type receptor counterpart to generate a heteromeric signaling complex. Type I receptors are referred to as the Activin Receptor-like Kinases (ALKs), while the type II receptors are named for the ligands they bind.
Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
Chemical Name: | 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide |
Purity: | ≥99% (HPLC) |
SB 431542 synthesized to cGMP guidelines
Chemical Name: | 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide |
Purity: | ≥99% |
Selective inhibitor of TGF-βRI, ALK4 and ALK7
Chemical Name: | 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide |
Purity: | ≥98% (HPLC) |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #3U6I8 |
Applications: | IHC, WB, ICC/IF |
Source: | NS0 |
Accession #: | AAA60556 |
Applications: | Bind |
Source: | NS0 |
Accession #: | NP_031421 |
Applications: | Bind |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #544310 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #544310 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #544310 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #544310 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #544310 |
Applications: | Flow |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #JE38-48 |
Applications: | IHC, WB, ICC/IF, Flow |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #S08-8D6 |
Applications: | WB, ICC/IF |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #544310 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #544310 |
Applications: | Flow |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #S07-7H9 |
Applications: | WB |
Applications: | AC |
Applications: | WB |
Reactivity: | Human |
Details: | Mouse IgG2B Monoclonal Clone #544310 |
Applications: | Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG2B Monoclonal Clone #544310 |
Applications: | Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG2B Monoclonal Clone #544310 |
Applications: | Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG2B Monoclonal Clone #544310 |
Applications: | Flow, CyTOF-ready |