ALK/CD246 Products
Anaplastic Lymphoma Kinase (ALK), also known as CD246, is a 220 kDa transmembrane glycoprotein that is primarily expressed in the developing nervous system. ALK contains one LDL Receptor (LDLR) class A domain, two meprin/A5-protein/PTPmu (MAM) domains, and a cytoplasmic kinase domain. Chromosomal translocation involving ALK and the nucleolar NPM protein result in a cytoplasmic fusion protein that exists as a dimer. The kinase domain in NPM-ALK is constitutively active and participates in cellular transformation. ALK translocations are found in a variety of tumors. Within the extracellular domain, human and mouse ALK share 88% amino acid sequence identity.
30 results for "ALK/CD246" in Products
30 results for "ALK/CD246" in Products
ALK/CD246 Products
Anaplastic Lymphoma Kinase (ALK), also known as CD246, is a 220 kDa transmembrane glycoprotein that is primarily expressed in the developing nervous system. ALK contains one LDL Receptor (LDLR) class A domain, two meprin/A5-protein/PTPmu (MAM) domains, and a cytoplasmic kinase domain. Chromosomal translocation involving ALK and the nucleolar NPM protein result in a cytoplasmic fusion protein that exists as a dimer. The kinase domain in NPM-ALK is constitutively active and participates in cellular transformation. ALK translocations are found in a variety of tumors. Within the extracellular domain, human and mouse ALK share 88% amino acid sequence identity.
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #RM361 |
| Applications: | IHC, WB |
![Western Blot: ALK/CD246 Antibody (RM361) [NBP2-77424]](https://resources.bio-techne.com/images/products/ALK-CD246-Antibody-RM361-Western-Blot-NBP2-77424-img0003.jpg "Western Blot: ALK/CD246 Antibody (RM361) [NBP2-77424]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: ALK/CD246 Antibody [NBP2-48518]](https://resources.bio-techne.com/images/products/ALK-CD246-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-48518-img0002.jpg "Immunocytochemistry/ Immunofluorescence: ALK/CD246 Antibody [NBP2-48518]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: ALK/CD246 Antibody (ALK1/2766R) [NBP3-07772]](https://resources.bio-techne.com/images/products/ALK-CD246-Antibody-ALK1-2766R-Immunohistochemistry-Paraffin-NBP3-07772-img0001.jpg "Immunohistochemistry-Paraffin: ALK/CD246 Antibody (ALK1/2766R) [NBP3-07772]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #ALK1/2766R |
| Applications: | IHC |