alpha-2A Adrenergic R/ADRA2A Products
Alpha-2-adrenergic receptors, including ADRA2A, are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both ADRA2A and ADRA2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The ADRA2A subtype inhibited transmitter release at high stimulation frequencies, whereas the ADRA2C subtype modulated neurotransmission at lower levels of nerve activity.
54 results for "alpha-2A Adrenergic R/ADRA2A" in Products
54 results for "alpha-2A Adrenergic R/ADRA2A" in Products
alpha-2A Adrenergic R/ADRA2A Products
Alpha-2-adrenergic receptors, including ADRA2A, are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both ADRA2A and ADRA2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The ADRA2A subtype inhibited transmitter release at high stimulation frequencies, whereas the ADRA2C subtype modulated neurotransmission at lower levels of nerve activity.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1006614 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: alpha-2A Adrenergic R/ADRA2A Antibody [NBP2-22452]](https://resources.bio-techne.com/images/products/alpha-2A "Western Blot: alpha-2A Adrenergic R/ADRA2A Antibody [NBP2-22452]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1006614 |
| Applications: | Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1006614 |
| Applications: | Flow |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | ELISA, ICC/IF, Flow |
![Immunocytochemistry/ Immunofluorescence: alpha-2A Adrenergic R/ADRA2A Antibody [NB100-2819]](https://resources.bio-techne.com/images/products/alpha-2A-Adrenergic-R-ADRA2A-Antibody-Immunocytochemistry-Immunofluorescence-NB100-2819-img0001.jpg "Immunocytochemistry/ Immunofluorescence: alpha-2A Adrenergic R/ADRA2A Antibody [NB100-2819]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1006614 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1006614 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1006614 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1006614 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1006614 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | WB |
![Western Blot: alpha-2A Adrenergic R/ADRA2A Antibody [NBP3-10657]](https://resources.bio-techne.com/images/products/alpha-2A-Adrenergic-R-ADRA2A-Antibody-Western-Blot-NBP3-10657-img0001.jpg "Western Blot: alpha-2A Adrenergic R/ADRA2A Antibody [NBP3-10657]")
| Applications: | AP |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1006614 |
| Applications: | Flow, CyTOF-ready |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% (HPLC) |
Selective α2 antagonist
| Chemical Name: | 17α-Hydroxyyohimban-16α-carboxylic acid methyl ester hydrochloride |
| Purity: | ≥98% (HPLC) |
α2A agonist
| Chemical Name: | [(2,6-Dichlorophenyl)acetyl]guanidine hydrochloride |
| Purity: | ≥99% (HPLC) |
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant
| Alternate Names: | Org 3770,6-Azamianserin |
| Chemical Name: | 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine |
| Purity: | ≥99% (HPLC) |
α2 agonist. Also I1 ligand
| Chemical Name: | 2-[(2,6-Dichlorophenyl)amino-2-imidazoline hydrochloride |
| Purity: | ≥99% (HPLC) |
Potent, selective α2D antagonist
| Chemical Name: | 2-(2,3-Dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole hydrochloride |
| Purity: | ≥99% (HPLC) |
Potent and non-selective β antagonist; also potent α1 antagonist
| Alternate Names: | BM 14190 |
| Chemical Name: | 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol |
| Purity: | ≥98% (HPLC) |
Potent and selective α2 antagonist
| Chemical Name: | 6-Chloro-N-methyl-2,3,4,5-tetrahydro-1-H-3-benzazepine hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective α2 antagonist
| Chemical Name: | 5-(2-Ethyl-2,3-dihydro-1H-indene-2-yl)-1H-imidazole hydrochloride |
| Purity: | ≥99% (HPLC) |
Potent and selective α2 antagonist
| Chemical Name: | (8aR,12aS,13aS)-5,8,8a,9,10,11,12,12a,13,13a-dechydro-3-methoxy-12-(ethylsulfonyl)-6H-isoquino[2,1-g][1,6]naphthyridine hydrochloride |
| Purity: | ≥99% (HPLC) |
