Bcl-xL Products
Bcl-x is a member of the Bcl-2 family of proteins that regulates outer mitochondrial membrane permeability. Alternative splicing results in two distinct Bcl-x isoforms. Bcl-xL (long) is an anti-apoptotic protein that prevents release of Cytochromec from the mitochondrial intermembrane space into the cytosol. Bcl-xs (short) is a pro-apoptotic member that can initiate programmed cell death.
123 results for "Bcl-xL" in Products
123 results for "Bcl-xL" in Products
Bcl-xL Products
Bcl-x is a member of the Bcl-2 family of proteins that regulates outer mitochondrial membrane permeability. Alternative splicing results in two distinct Bcl-x isoforms. Bcl-xL (long) is an anti-apoptotic protein that prevents release of Cytochromec from the mitochondrial intermembrane space into the cytosol. Bcl-xs (short) is a pro-apoptotic member that can initiate programmed cell death.
Blue-fluorescent dye for DNA staining. Cell permeable. Used for: nuclear counterstain, apoptosis analysis, fixed and live-cell staining. Application: flow cytometry, confocal microscopy
| Chemical Name: | 2'-(4-Ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole trihydrochloride |
| Applications: | Flow |
| Purity: | ≥98% (HPLC) |
| Assay Range: | 625 - 20,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Rat, Canine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
![Western Blot: Bcl-xL Antibody [NB100-56104]](https://resources.bio-techne.com/images/products/Bcl-xL-Antibody-Western-Blot-NB100-56104-img0007.jpg "Western Blot: Bcl-xL Antibody [NB100-56104]")
Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #2052A |
| Applications: | WB, Simple Western, IHC |
| Source: | E. coli |
| Accession #: | CAA80661 |
| Applications: | InhibAct |
High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor
| Chemical Name: | 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide |
| Purity: | ≥98% (HPLC) |
Potent and selective Bcl-xL inhibitor; antitumor and inducer of apoptosis
| Chemical Name: | 6-[8-[(2-Benzothiazolylamino)carbonyl]-3,4-dihydro-2(1H)-isoquinolinyl]-3-[5-methyl-1-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-pyrazol-4-yl]-2-pyridinecarboxylic acid |
| Purity: | ≥98% (HPLC) |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat, Canine, Feline |
| Details: | Rabbit IgG Monoclonal Clone #HL2038 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #OTI4A9 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Bcl-xL Antibody (OTI4A9) [NBP1-47665]](https://resources.bio-techne.com/images/products/Bcl-xL-Antibody-4A9-Western-Blot-NBP1-47665-img0008.jpg "Western Blot: Bcl-xL Antibody (OTI4A9) [NBP1-47665]")
| Reactivity: | Human, Mouse, Rat, Rhesus Macaque |
| Details: | Mouse IgG3 Kappa Monoclonal Clone #7B2.5 |
| Applications: | WB, Flow, IP |
![Flow Cytometry: Bcl-xL Antibody (7B2.5) [NBP1-28559]](https://resources.bio-techne.com/images/products/Bcl-xL-Antibody-7B2-5-Flow-Cytometry-NBP1-28559-img0004.jpg "Flow Cytometry: Bcl-xL Antibody (7B2.5) [NBP1-28559]")
Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines
| Chemical Name: | 4-[4-[(4'-Chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide |
| Purity: | ≥98% (HPLC) |
| Source: | E. coli |
| Accession #: | Q64373 |
| Applications: | InhibAct |
Proapoptotic; downregulates Bcl-2 and Bcl-XL
| Chemical Name: | 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Canine, Feline, Human, Sheep |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF (-), WB |
Inhibitor of Bcl-2 family members; antiapoptotic
| Alternate Names: | GX15-070 |
| Chemical Name: | 2-[2-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene)-3-methoxy-2H-pyrrol-5-yl]-1H-indole methanesulfonate |
| Purity: | ≥98% (HPLC) |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #016 |
| Applications: | WB, ELISA, IP |
![Western Blot: Bcl-xL Antibody (016) [NBP2-89507]](https://resources.bio-techne.com/images/products/Bcl-xL-Antibody-016-Western-Blot-NBP2-89507-img0002.jpg "Western Blot: Bcl-xL Antibody (016) [NBP2-89507]")
| Applications: | AC |
Cell-permeable protein kinase C inhibitor
| Chemical Name: | 1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium chloride |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: Bcl-xL Antibody [NBP2-38262]](https://resources.bio-techne.com/images/products/Bcl-xL-Antibody-Western-Blot-NBP2-38262-img0003.jpg "Western Blot: Bcl-xL Antibody [NBP2-38262]")
| Applications: | ELISA |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #C4 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #C2 |
| Applications: | IHC, WB, ICC/IF |
| Applications: | WB |
![Western Blot: Bcl-xL Overexpression Lysate [NBL1-07946]](https://resources.bio-techne.com/images/products/Bcl-Xl-Overexpression-Lysate-Native-Western-Blot-NBL1-07946-img0003.jpg "Western Blot: Bcl-xL Overexpression Lysate [NBL1-07946]")
| Applications: | WB |
![Western Blot: Bcl-xL Overexpression Lysate [NBP2-08227]](https://resources.bio-techne.com/images/products/Bcl-Xl-Overexpression-Lysate-Native-Western-Blot-NBP2-08227-img0002.jpg "Western Blot: Bcl-xL Overexpression Lysate [NBP2-08227]")