beta-1 Adrenergic R/ADRB1 Products
The beta-1 Adrenergic Receptor (ADRB1) belongs to the G protein-coupled receptor 1 family. The adrenergic receptors, including ADRB1, are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. ADRB1 binds epinephrine and norepinephrine with approximately equal affinity. ADRB1 is localized at the plasma membrane. It is also found in the Golgi upon Golgi-associated PDZ and coiled-coil motif-containing protein (GOPC) overexpression. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.
16 results for "beta-1 Adrenergic R/ADRB1" in Products
16 results for "beta-1 Adrenergic R/ADRB1" in Products
beta-1 Adrenergic R/ADRB1 Products
The beta-1 Adrenergic Receptor (ADRB1) belongs to the G protein-coupled receptor 1 family. The adrenergic receptors, including ADRB1, are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. ADRB1 binds epinephrine and norepinephrine with approximately equal affinity. ADRB1 is localized at the plasma membrane. It is also found in the Golgi upon Golgi-associated PDZ and coiled-coil motif-containing protein (GOPC) overexpression. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, ELISA, Func |
![Western Blot: beta-1 Adrenergic R/ADRB1 Antibody [NB600-978]](https://resources.bio-techne.com/images/products/beta-1 "Western Blot: beta-1 Adrenergic R/ADRB1 Antibody [NB600-978]")
| Applications: | AC |
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: beta-1 Adrenergic R/ADRB1 AntibodyAzide and BSA Free [NBP3-16089]](https://resources.bio-techne.com/images/products/beta-1-Adrenergic-R-ADRB1-Antibody-Western-Blot-NBP3-16089-img0001.jpg "Western Blot: beta-1 Adrenergic R/ADRB1 AntibodyAzide and BSA Free [NBP3-16089]")
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2203D |
| Applications: | WB |
Standard selective β agonist
| Alternate Names: | Isoprenaline |
| Chemical Name: | 4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol hydrochloride |
| Purity: | ≥98% (HPLC) |
Highly selective β1-adrenoceptor antagonist
| Chemical Name: | (±)-[2R*(1S*5S*(S*))]-α,α'-[Iminobis(methylene)bis(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol) |
| Purity: | ≥98% (HPLC) |
Potent and non-selective β antagonist; also potent α1 antagonist
| Alternate Names: | BM 14190 |
| Chemical Name: | 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol |
| Purity: | ≥98% (HPLC) |
Selective β1 antagonist
| Chemical Name: | 1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol hemitartrate |
| Purity: | ≥99% (HPLC) |
α1, β1 and β2 agonist
| Chemical Name: | 4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]aminoethyl-1,2-benzenediol hydrochloride |
| Purity: | ≥98% (HPLC) |
β antagonist
| Chemical Name: | (RS)-1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride |
5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist
| Chemical Name: | 4-[3-[tert-Butylamino]-2-hydroxypropoxy]-1H-indole-2-carbonitrile hemifumarate |
| Purity: | ≥98% (HPLC) |
Highly potent and selective β1 antagonist
| Chemical Name: | 1-[2-((3-Carbamoyl-4-hydroxy)phenoxy)ethylamino]-3-[4-(1-methyl-4-trifluoromethyl-2-imidazolyl)phenoxy]-2-propanol dihydrochloride |
| Purity: | ≥96% (HPLC) |
Selective β1 partial agonist
| Alternate Names: | ICI 118,587 |
| Chemical Name: | 1-(4-Hydroxyphenoxy)-3-[2-(4-morpholinocarboxamido)ethylamino]-2-propanol hemifumarate |
| Purity: | ≥97% (HPLC) |
