DOT1L Products
DOT1L (mammalian counterpart of yeast Dot1) is a nuclear non-SET domain histone H3K79 methyltransferase. It is involved in developmental gene transcription and maintenance of chromatin structure, and may promote mixed lineage leukemia.
26 results for "DOT1L" in Products
26 results for "DOT1L" in Products
DOT1L Products
DOT1L (mammalian counterpart of yeast Dot1) is a nuclear non-SET domain histone H3K79 methyltransferase. It is involved in developmental gene transcription and maintenance of chromatin structure, and may promote mixed lineage leukemia.
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, IP, ChIP, +1 More |
![Western Blot: DOT1L Antibody [NB100-40845]](https://resources.bio-techne.com/images/products/DOT1L-Antibody-Western-Blot-NB100-40845-img0014.jpg "Western Blot: DOT1L Antibody [NB100-40845]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #653613 |
| Applications: | IHC, IP |
| Reactivity: | Human, Feline |
| Details: | Mouse IgG1 kappa Monoclonal Clone #6A6 |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: DOT1L Antibody (6A6) [H00084444-M01]](https://resources.bio-techne.com/images/products/DOT1L-Antibody-6A6-Western-Blot-H00084444-M01-img0005.jpg "Western Blot: DOT1L Antibody (6A6) [H00084444-M01]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1D8 |
| Applications: | IHC, WB |
![Western Blot: DOT1L Antibody (OTI1D8) [NBP2-46473]](https://resources.bio-techne.com/images/products/DOT1L-Antibody-1D8-Western-Blot-NBP2-46473-img0003.jpg "Western Blot: DOT1L Antibody (OTI1D8) [NBP2-46473]")
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #OTI6E7 |
| Applications: | IHC, WB |
![Western Blot: DOT1L Antibody (OTI6E7) [NBP2-46474]](https://resources.bio-techne.com/images/products/DOT1L-Antibody-6E7-Western-Blot-NBP2-46474-img0003.jpg "Western Blot: DOT1L Antibody (OTI6E7) [NBP2-46474]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #PSH01-57 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IP |
![Immunoprecipitation: DOT1L Antibody [NB100-40846]](https://resources.bio-techne.com/images/products/DOT1L-Antibody-Immunoprecipitation-NB100-40846-img0002.jpg "Immunoprecipitation: DOT1L Antibody [NB100-40846]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #7A10H9 |
| Applications: | WB, IP |
![Western Blot: DOT1L Antibody (7A10H9) [NBP3-15446]](https://resources.bio-techne.com/images/products/DOT1L-Antibody-7A10H9-Western-Blot-NBP3-15446-img0001.jpg "Western Blot: DOT1L Antibody (7A10H9) [NBP3-15446]")
| Applications: | WB, ELISA, MA, AP |
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #3B6 |
| Applications: | WB, ELISA |
![Western Blot: DOT1L Antibody (3B6) [NBP3-15150]](https://resources.bio-techne.com/images/products/DOT1L-Antibody-3B6-Western-Blot-NBP3-15150-img0001.jpg "Western Blot: DOT1L Antibody (3B6) [NBP3-15150]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: DOT1L Antibody [NBP3-21378] -](https://resources.bio-techne.com/images/products/nbp3-21378_rabbit-dot1l-pab-45202315534312.jpg "Immunohistochemistry-Paraffin: DOT1L Antibody [NBP3-21378] -")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: DOT1L Antibody [NBP2-55244]](https://resources.bio-techne.com/images/products/DOT1L-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-55244-img0001.jpg "Immunocytochemistry/ Immunofluorescence: DOT1L Antibody [NBP2-55244]")
| Applications: | AC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1D8 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1D8 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1D8 |
| Applications: | IHC, WB |
Highly potent and selective DOT1L inhibitor; cell permeable
| Chemical Name: | 1-[3-[[[(2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl](isopropyl)amino]propyl]-3-[4-(2,2-dimethylethyl)phenyl]urea |
| Purity: | ≥99% (HPLC) |
Highly potent DOT1L inhibitor
| Chemical Name: | 7-[5-Deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1D8 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1D8 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #OTI6E7 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #OTI6E7 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #OTI6E7 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #OTI6E7 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1D8 |
| Applications: | IHC, WB |