ErbB2/Her2 Products
ErbB2, also called Neu and Her2, is a transmembrane glycoprotein in the ErbB family of tyrosine kinase receptors for EGF superfamily growth factors. ErbB2 is widely expressed in epithelial cells and over-expressed in a large number of breast carcinomas. ErbB2 has no identified ligands but heterodimerizes with ErbB1/EGF R, ErbB3, or ErbB4 to form higher affinity signaling complexes. The protease ADAM10 releases a 110 kDa soluble fragment of ErbB2 from the cell surface. ErbB2 plays roles in development, cancer, communication at the neuromuscular junction, and regulation of cell growth and differentiation. The ErbB2/ErbB3 heterodimer is expressed in the majority of breast, skin, ovary and gastrointestinal tumors and transduces a highly mitogenic signal in response to neuregulin 1 (NRG1; heuregulin 1) or NRG2. ErbB3, ErbB2 and neuregulin are all required for formation of the sympathetic nervous system.
1015 results for "ErbB2/Her2" in Products
1015 results for "ErbB2/Her2" in Products
ErbB2/Her2 Products
ErbB2, also called Neu and Her2, is a transmembrane glycoprotein in the ErbB family of tyrosine kinase receptors for EGF superfamily growth factors. ErbB2 is widely expressed in epithelial cells and over-expressed in a large number of breast carcinomas. ErbB2 has no identified ligands but heterodimerizes with ErbB1/EGF R, ErbB3, or ErbB4 to form higher affinity signaling complexes. The protease ADAM10 releases a 110 kDa soluble fragment of ErbB2 from the cell surface. ErbB2 plays roles in development, cancer, communication at the neuromuscular junction, and regulation of cell growth and differentiation. The ErbB2/ErbB3 heterodimer is expressed in the majority of breast, skin, ovary and gastrointestinal tumors and transduces a highly mitogenic signal in response to neuregulin 1 (NRG1; heuregulin 1) or NRG2. ErbB3, ErbB2 and neuregulin are all required for formation of the sympathetic nervous system.
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Immunohistochemistry-Paraffin: ErbB2/Her2 [p Tyr1222, p Tyr1221] Antibody [NBP3-13232]](https://resources.bio-techne.com/images/products/ErbB2-Her2-[p-Tyr1222--p-Tyr1221]-Antibody-Immunohistochemistry-Paraffin-NBP3-13232-img0002.jpg "Immunohistochemistry-Paraffin: ErbB2/Her2 [p Tyr1222, p Tyr1221] Antibody [NBP3-13232]")
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Applications: | WB, ELISA, Func, MA, AP |
![SDS-PAGE: Recombinant Human ErbB2/Her2 GST (N-Term) Protein [H00002064-P01]](https://resources.bio-techne.com/images/products/Recombinant-Human-ErbB2-Her2-Protein-SDS-Page-H00002064-P01-img0002.jpg "SDS-PAGE: Recombinant Human ErbB2/Her2 GST (N-Term) Protein [H00002064-P01]")
Clone 24D2 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #24D2 |
| Applications: | ICC/IF, Flow |
![Flow Cytometry: ErbB2/Her2 Antibody (24D2) - BSA Free [NBP3-09136]](https://resources.bio-techne.com/images/products/ErbB2-Her2-Antibody-24D2-Flow-Cytometry-NBP3-09136-img0001.jpg "Flow Cytometry: ErbB2/Her2 Antibody (24D2) - BSA Free [NBP3-09136]")
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #666521 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #191924 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![ErbB2/Her2 [p Tyr877] Antibody - BSA Free](https://resources.bio-techne.com/images/products/nb100-81961_rabbit-polyclonal-erbb2-her2-p-tyr877-antibody-113202515145437.jpg "Immunocytochemistry/Immunofluorescence: ErbB2/Her2 [p Tyr877] Antibody [NB100-81961] -")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #PD00-53 |
| Applications: | IHC, WB, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #ERB2/776 |
| Applications: | IHC, ICC/IF, ELISA, Flow |
![Immunocytochemistry/ Immunofluorescence: ErbB2/Her2 Antibody (ERB2/776) [NBP2-44983]](https://resources.bio-techne.com/images/products/ErbB2-Her2-Antibody-ERB2-776-Immunocytochemistry-Immunofluorescence-NBP2-44983-img0004.jpg "Immunocytochemistry/ Immunofluorescence: ErbB2/Her2 Antibody (ERB2/776) [NBP2-44983]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL0268 |
| Applications: | IHC, WB |
![Western Blot: ErbB2/Her2 Antibody (CL0268) [NBP2-52896]](https://resources.bio-techne.com/images/products/ErbB2-Her2-Antibody-CL0268-Western-Blot-NBP2-52896-img0006.jpg "Western Blot: ErbB2/Her2 Antibody (CL0268) [NBP2-52896]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #191924 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #191924 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #666521 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #666521 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #191924 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #666521 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #191924 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #666521 |
| Applications: | Flow |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #HRB2/718 |
| Applications: | ICC/IF, ELISA, Flow, MA |
![Immunocytochemistry/ Immunofluorescence: ErbB2/Her2 Antibody (HRB2/718) [NBP2-32864]](https://resources.bio-techne.com/images/products/ErbB2-Her2-Antibody-HRB2-718-Immunocytochemistry-Immunofluorescence-NBP2-32864-img0005.jpg "Immunocytochemistry/ Immunofluorescence: ErbB2/Her2 Antibody (HRB2/718) [NBP2-32864]")
For use with catalog number DHER20
| Applications: | Ctrl |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #002 |
| Applications: | IHC, ICC/IF, ELISA |
![Immunocytochemistry/ Immunofluorescence: ErbB2/Her2 Antibody (002) [NBP2-89184]](https://resources.bio-techne.com/images/products/ErbB2-Her2-Antibody-002-Immunocytochemistry-Immunofluorescence-NBP2-89184-img0001.jpg "Immunocytochemistry/ Immunofluorescence: ErbB2/Her2 Antibody (002) [NBP2-89184]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #511 |
| Applications: | ICC/IF, ELISA, Flow |
![Immunocytochemistry/ Immunofluorescence: ErbB2/Her2 Antibody (511) [NBP2-89187]](https://resources.bio-techne.com/images/products/ErbB2-Her2-Antibody-511-Immunocytochemistry-Immunofluorescence-NBP2-89187-img0001.jpg "Immunocytochemistry/ Immunofluorescence: ErbB2/Her2 Antibody (511) [NBP2-89187]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #HRB2/258 |
| Applications: | ICC/IF, ELISA, Flow |
![Flow Cytometry: ErbB2/Her2 Antibody (HRB2/258) [NBP2-32862]](https://resources.bio-techne.com/images/products/ErbB2-Her2-Antibody-HRB2-258-Flow-Cytometry-NBP2-32862-img0002.jpg "Flow Cytometry: ErbB2/Her2 Antibody (HRB2/258) [NBP2-32862]")
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #666521 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #666521 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Immunohistochemistry-Paraffin: ErbB2/Her2 Antibody - BSA Free [NBP3-02960]](https://resources.bio-techne.com/images/products/ErbB2-Her2-Antibody-Immunohistochemistry-Paraffin-NBP3-02960-img0007.jpg "Immunohistochemistry-Paraffin: ErbB2/Her2 Antibody - BSA Free [NBP3-02960]")
| Reactivity: | Human |
| Details: | Human IgG1 kappa Monoclonal Clone #4D5-8 (trastuzumab) |
| Applications: | IHC, ELISA, Flow |
![Immunohistochemistry: ErbB2/Her2 Antibody (4D5-8 (trastuzumab)) - Azide and BSA Free [NBP2-75895]](https://resources.bio-techne.com/images/products/ErbB2-Her2-Antibody-4D5-8-trastuzumab-Immunohistochemistry-NBP2-75895-img0001.jpg "Immunohistochemistry: ErbB2/Her2 Antibody (4D5-8 (trastuzumab)) - Azide and BSA Free [NBP2-75895]")
| Applications: | AC |
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #666521 |
| Applications: | Flow, CyTOF-ready |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #JE60-90 |
| Applications: | WB, ICC/IF, Flow |
![ErbB2/Her2 [p Tyr1139] Antibody (JE60-90)](https://resources.bio-techne.com/images/products/nbp3-32768_rabbit-erbb2-her2-p-tyr1139-mab-je60-90-288202412442922.jpg "Western Blot: ErbB2/Her2 [p Tyr1139] Antibody (JE60-90) [NBP3-32768]")
Recombinant Monoclonal Antibody
| Applications: | ELISA |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #PSH04-03 |
| Applications: | WB, ICC/IF |
![ErbB2/Her2 [p Tyr1248] Antibody (PSH04-03)](https://resources.bio-techne.com/images/products/nbp3-32770_rabbit-erbb2-her2-p-tyr1248-mab-psh04-03-288202412461670.jpg "Western Blot: ErbB2/Her2 [p Tyr1248] Antibody (PSH04-03) [NBP3-32770]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #PD00-99 |
| Applications: | IHC, WB |
| Applications: | AC |
| Applications: | WB |
![Western Blot: ErbB2/Her2 Overexpression Lysate [NBL1-10314]](https://resources.bio-techne.com/images/products/ErbB2-HER2-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-10314-img0002.jpg "Western Blot: ErbB2/Her2 Overexpression Lysate [NBL1-10314]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: ErbB2/Her2 Antibody [NBP2-55546]](https://resources.bio-techne.com/images/products/ErbB2-Her2-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-55546-img0001.jpg "Immunocytochemistry/ Immunofluorescence: ErbB2/Her2 Antibody [NBP2-55546]")
| Applications: | AC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #205 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #666521 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #666521 |
| Applications: | Flow, CyTOF-ready |