GDF-5/BMP-14 Products
Growth Differentiation Factor-5, also known as BMP-14 and CDMP-1, is a member of the BMP family of TGF-beta superfamily proteins. GDF-5 signaling is mediated by formation of a heterodimeric complex consisting of a type 1 (BMPR-IB) and a type II (BMPR-II or Activin RII) serine/threonine kinase receptor which results in the phosphorylation and activation of cytosolic Smad proteins (Smad1, 5, and 8). Its signaling is antagonized by Noggin. GDF-5 is involved in multiple developmental processes including limb generation, cartilage development, joint formation, bone morphogenesis, cell survival, and neuritogenesis. GDF-5 can promote chondrogenesis, osteogenesis, and angiogenesis in mesenchymal stem cells.
Products:
53 results for "GDF-5/BMP-14" in Products
53 results for "GDF-5/BMP-14" in Products
GDF-5/BMP-14 Products
Growth Differentiation Factor-5, also known as BMP-14 and CDMP-1, is a member of the BMP family of TGF-beta superfamily proteins. GDF-5 signaling is mediated by formation of a heterodimeric complex consisting of a type 1 (BMPR-IB) and a type II (BMPR-II or Activin RII) serine/threonine kinase receptor which results in the phosphorylation and activation of cytosolic Smad proteins (Smad1, 5, and 8). Its signaling is antagonized by Noggin. GDF-5 is involved in multiple developmental processes including limb generation, cartilage development, joint formation, bone morphogenesis, cell survival, and neuritogenesis. GDF-5 can promote chondrogenesis, osteogenesis, and angiogenesis in mesenchymal stem cells.
Products:
| Source: | E. coli |
| Accession #: | P43027 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Source: | E. coli |
| Accession #: | P43026 |
| Applications: | BA |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #90509 |
| Applications: | WB, IHC |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #90509 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #143004 |
| Applications: | Neut |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: GDF-5/BMP-14 Antibody [NBP1-88575]](https://resources.bio-techne.com/images/products/GDF-5-BMP-14-Antibody-Western-Blot-NBP1-88575-img0005.jpg "Western Blot: GDF-5/BMP-14 Antibody [NBP1-88575]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #1065032 |
| Applications: | ICC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Func |
![Western Blot: GDF-5/BMP-14 Antibody [NBP2-16631]](https://resources.bio-techne.com/images/products/GDF5-Antibody-Western-Blot-NBP2-16631-img0001.jpg "Western Blot: GDF-5/BMP-14 Antibody [NBP2-16631]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: GDF-5/BMP-14 Antibody [NBP2-16632]](https://resources.bio-techne.com/images/products/GDF-5-BMP-14-Antibody-Western-Blot-NBP2-16632-img0006.jpg "Western Blot: GDF-5/BMP-14 Antibody [NBP2-16632]")
| Applications: | WB |
![Western Blot: GDF-5/BMP-14 Overexpression Lysate [NBL1-11027]](https://resources.bio-techne.com/images/products/GDF5-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-11027-img0002.jpg "Western Blot: GDF-5/BMP-14 Overexpression Lysate [NBL1-11027]")
| Applications: | ELISA |
| Applications: | AC |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0242-13J15 |
| Applications: | WB, B/N |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0242-13J15 |
| Applications: | WB, B/N |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0242-13J15 |
| Applications: | WB, B/N |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0242-13J15 |
| Applications: | WB, B/N |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0242-13J15 |
| Applications: | WB, B/N |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0242-13J15 |
| Applications: | WB, B/N |
| Applications: | Bioactivity |