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HGFR/c-MET Products

HGFR (Hepatocyte Growth Factor Receptor), also known as Met, is a receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. In the absence of ligand, HGFR forms noncovalent complexes with a variety of membrane proteins including CD44v6, CD151, EGFR, Fas, Integrin alpha 6 beta 4, Plexins B1, 2, 3, and MSPR/Ron.

Ligation of one complex component triggers activation of the other, followed by cooperative signaling effects. Formation of some of these heteromeric complexes is a requirement for epithelial cell morphogenesis and tumor cell invasion. Paracrine induction of epithelial cell scattering and branching tubulogenesis results from the stimulation of HGFR on undifferentiated epithelium by HGF released from neighboring mesenchymal cells.

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460 results for "HGFR/c-MET" in Products

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460 results for "HGFR/c-MET" in Products

HGFR/c-MET Products

HGFR (Hepatocyte Growth Factor Receptor), also known as Met, is a receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. In the absence of ligand, HGFR forms noncovalent complexes with a variety of membrane proteins including CD44v6, CD151, EGFR, Fas, Integrin alpha 6 beta 4, Plexins B1, 2, 3, and MSPR/Ron.

Ligation of one complex component triggers activation of the other, followed by cooperative signaling effects. Formation of some of these heteromeric complexes is a requirement for epithelial cell morphogenesis and tumor cell invasion. Paracrine induction of epithelial cell scattering and branching tubulogenesis results from the stimulation of HGFR on undifferentiated epithelium by HGF released from neighboring mesenchymal cells.

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Applications: WB, Simple Western, Flow, IHC, Block, CyTOF-ready, ICC, KO
Reactivity: Human
Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: Flow
Reactivity: Human
Applications: WB, Simple Western, IHC, CyTOF-reported, ICC, ICFlow
Reactivity: Human, Mouse
Applications: Flow, CyTOF-ready
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: WB, Flow
Reactivity: Human
Applications: IHC, ICC
Reactivity: Human
Applications: WB, KO
Reactivity: Human
Applications: WB, IHC, ICC
Reactivity: Human, Mouse
Applications: IHC, WB, Flow, IP, KD
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: WB, Block
Reactivity: Canine
Applications: Flow
Reactivity: Human
Applications: WB, IHC, ICC
Reactivity: Human

(HEK293-expressed)

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