HVEM/TNFRSF14 Products
HVEM/TNFRSF14 (herpesvirus entry mediator) is a transmembrane protein that is most highly expressed on naïve, memory, and regulatory T cells but declines during T cell activation. It is present at low levels on most resting leukocytes. HVEM is a receptor for BTLA, CD160, and LIGHT.
A cis interaction between HVEM and BTLA promotes cell survival, while trans interaction promotes a state of lymphocyte inactivity. LIGHT is expressed following T cell activation and competes with BTLA for HVEM binding, leading to a proinflammatory response. The herpesvirus envelope glycoprotein gD, which binds HVEM to initiate membrane fusion, can antagonize both BTLA and LIGHT binding. Human, but not mouse, HVEM can also bind lymphotoxin-alpha.
Products:
154 results for "HVEM/TNFRSF14" in Products
154 results for "HVEM/TNFRSF14" in Products
HVEM/TNFRSF14 Products
HVEM/TNFRSF14 (herpesvirus entry mediator) is a transmembrane protein that is most highly expressed on naïve, memory, and regulatory T cells but declines during T cell activation. It is present at low levels on most resting leukocytes. HVEM is a receptor for BTLA, CD160, and LIGHT.
A cis interaction between HVEM and BTLA promotes cell survival, while trans interaction promotes a state of lymphocyte inactivity. LIGHT is expressed following T cell activation and competes with BTLA for HVEM binding, leading to a proinflammatory response. The herpesvirus envelope glycoprotein gD, which binds HVEM to initiate membrane fusion, can antagonize both BTLA and LIGHT binding. Human, but not mouse, HVEM can also bind lymphotoxin-alpha.
Products:
Control for use with Human HVEM/TNFRSF14 Simple Plex Cartridge Kit
Applications: | Ctrl, Simple Plex |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, IHC |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #94801 |
Applications: | WB, Flow, CyTOF-ready |
His-tag
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #2742B |
Applications: | Flow, Neut |
Source: | HEK293 |
Accession #: | Q92956.3 |
Applications: | BA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #94801 |
Applications: | Flow |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #2742B |
Applications: | Flow |
Recombinant Monoclonal Antibody.
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #2024B |
Applications: | Flow |
Recombinant Monoclonal Antibody.
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #2024B |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #94804 |
Applications: | IHC |
Source: | CHO |
Accession #: | NP_849262 |
Applications: | Bind |
Biotinylated
Source: | CHO |
Accession #: | Q92956.3 |
Applications: | BA |
Recombinant Monoclonal Antibody.
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #2024B |
Applications: | Flow |
Source: | HEK293 |
Accession #: | Q92956.3 |
Applications: | BA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #94801 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #94801 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #94801 |
Applications: | Flow |
Assay Range: | 15.6 - 1,000 pg/mL |
Applications: | ELISA |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #2742B |
Applications: | Flow |
Recombinant Monoclonal Antibody.
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #2024B |
Applications: | Flow |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #2742B |
Applications: | Flow |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #2742B |
Applications: | Flow |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #2742B |
Applications: | Flow |