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HVEM/TNFRSF14 Products

HVEM/TNFRSF14 (herpesvirus entry mediator) is a transmembrane protein that is most highly expressed on naïve, memory, and regulatory T cells but declines during T cell activation. It is present at low levels on most resting leukocytes. HVEM is a receptor for BTLA, CD160, and LIGHT.

A cis interaction between HVEM and BTLA promotes cell survival, while trans interaction promotes a state of lymphocyte inactivity. LIGHT is expressed following T cell activation and competes with BTLA for HVEM binding, leading to a proinflammatory response. The herpesvirus envelope glycoprotein gD, which binds HVEM to initiate membrane fusion, can antagonize both BTLA and LIGHT binding. Human, but not mouse, HVEM can also bind lymphotoxin-alpha.

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206 results for "HVEM/TNFRSF14" in Products

HVEM/TNFRSF14 Products

HVEM/TNFRSF14 (herpesvirus entry mediator) is a transmembrane protein that is most highly expressed on naïve, memory, and regulatory T cells but declines during T cell activation. It is present at low levels on most resting leukocytes. HVEM is a receptor for BTLA, CD160, and LIGHT.

A cis interaction between HVEM and BTLA promotes cell survival, while trans interaction promotes a state of lymphocyte inactivity. LIGHT is expressed following T cell activation and competes with BTLA for HVEM binding, leading to a proinflammatory response. The herpesvirus envelope glycoprotein gD, which binds HVEM to initiate membrane fusion, can antagonize both BTLA and LIGHT binding. Human, but not mouse, HVEM can also bind lymphotoxin-alpha.

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Applications: Simple Plex

Simple Plex Human HVEM/TNFRSF14 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: Ctrl, Simple Plex

Control for use with Human HVEM/TNFRSF14 Simple Plex Cartridge Kit

Applications: WB, Flow, CyTOF-ready
Reactivity: Human
Applications: WB, IHC
Reactivity: Human
Applications: Flow, Neut
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: IHC
Reactivity: Human

His-tag

Applications: BA
Applications: Flow
Reactivity: Human
Applications: Flow
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: Flow
Reactivity: Mouse

Recombinant Monoclonal Antibody.

Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse
Applications: BA

Biotinylated

Applications: Flow
Reactivity: Mouse

Recombinant Monoclonal Antibody.

Applications: Flow
Reactivity: Human
Applications: Flow
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: Flow
Reactivity: Mouse

Recombinant Monoclonal Antibody.

Applications: Flow
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: Flow
Reactivity: Mouse

Recombinant Monoclonal Antibody.

Applications: WB
Reactivity: Human
Applications: WB
Reactivity: Mouse
Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody.

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