IL-1 beta/IL-1F2 Products
IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.
257 results for "IL-1 beta/IL-1F2" in Products
257 results for "IL-1 beta/IL-1F2" in Products
IL-1 beta/IL-1F2 Products
IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.
Analyzed by SEC-MALS
| Source: | E. coli |
| Accession #: | NP_000567 |
| Applications: | BA |
Animal-Free.
| Source: | E. coli |
| Accession #: | NP_000567.1 |
| Applications: | BA |
| Sensitivity: | 1 pg/mL |
| Applications: | ELISA |
| Assay Range: | 3.9 - 250 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Assay Range: | 3.91 - 250 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey, +5 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, ELISA, Flow, +4 More |
![Western Blot: IL-1 beta/IL-1F2 Antibody [NB600-633]](https://resources.bio-techne.com/images/products/IL-1-beta-IL-1F2-Antibody-Western-Blot-NB600-633-img0012.jpg "Western Blot: IL-1 beta/IL-1F2 Antibody [NB600-633]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC, Dual ISH-IHC, ICC, +1 More |
| Sensitivity: | 0.063 pg/mL |
| Applications: | ELISA |
| Assay Range: | 0.125 - 8 pg/mL (Serum, EDTA Plasma, Heparin Plasma, Saliva) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #8516 |
| Applications: | WB, Simple Western, CyTOF-ready, ICC, ICFlow, +1 More |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #2805 |
| Applications: | WB, Simple Western, ICC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: IL-1 beta/IL-1F2 AntibodyBSA Free [NBP1-19775]](https://resources.bio-techne.com/images/products/IL-1-beta-IL-1F2-Antibody-Western-Blot-NBP1-19775-img0004.jpg "Western Blot: IL-1 beta/IL-1F2 AntibodyBSA Free [NBP1-19775]")
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #615417 |
| Applications: | WB, Simple Western, ICC |
| Sensitivity: | 0.55 pg/mL |
| Applications: | ELISA |
| Assay Range: | 1.4 - 1,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #43N3D8 |
| Applications: | IHC, WB, Flow |
![Western Blot: IL-1 beta/IL-1F2 Antibody (43N3D8)BSA Free [NBP2-27345]](https://resources.bio-techne.com/images/products/IL-1-beta-IL-1F2-Antibody-43N3D8-Western-Blot-NBP2-27345-img0008.jpg "Western Blot: IL-1 beta/IL-1F2 Antibody (43N3D8)BSA Free [NBP2-27345]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC, Neut |
Intended for preclinical researchers who may transition to GMP IL-1beta for their clinical work
| Source: | E. coli |
| Accession #: | NP_000567.1 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #8516 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #8516 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #8516 |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1027B |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #8516 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #8516 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #8516 |
| Applications: | ICFlow |