Jak2 Products
Jak1, Jak 2, and Jak3 belong to the Janus Kinases family of protein tyrosine kinases that couple to cytokine receptors once activated by their corresponding ligands. Activation of Jak family members occurs via phosphorylation at two adjacent tyrosine residues as well as potentially one or more serine residues. Jaks activate members of the STAT f...
4 results for "Jak2" in Products
4 results for "Jak2" in Products
Jak2 Products
Jak1, Jak 2, and Jak3 belong to the Janus Kinases family of protein tyrosine kinases that couple to cytokine receptors once activated by their corresponding ligands. Activation of Jak family members occurs via phosphorylation at two adjacent tyrosine residues as well as potentially one or more serine residues. Jaks activate members of the STAT f...
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG2B Monoclonal Clone #6-D3 |
Applications: | IHC, WB, ICC/IF, Flow, MA |
Reactivity: | Human, Insect |
Details: | Mouse IgG2b Kappa Monoclonal Clone #53B7 |
Applications: | WB, ELISA, ICC/IF, Flow, MA, +1 More |
Potent, selective inhibitor of MEK1 and 2
Chemical Name: | 1,4-Diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene |
Potent JAK inhibitor
Alternate Names: | Tofacitinib citrate |
Chemical Name: | (3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile citrate |
Purity: | ≥99% (HPLC) |