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M-CSF Products

M-CSF (CSF-1) is the primary regulator of macrophage survival, proliferation and differentiation. It is essential for macrophage-related functions such as bone resorption, vascular development, and innate immunity. It signals through M-CSF R on monocytes, tissue macrophages, and osteoblasts. Both M-CSF and its receptor can be expressed by tumor cells, allowing M-CSF to act as an autocrine growth factor for cancer cells. Full length M-CSF is expressed as a transmembrane dimer, but various additional forms can be generated by alternative splicing, differential glycosylation, chondroitin sulfate proteoglycan modification, and proteolytic shedding.

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93 results for "M-CSF" in Products

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93 results for "M-CSF" in Products

M-CSF Products

M-CSF (CSF-1) is the primary regulator of macrophage survival, proliferation and differentiation. It is essential for macrophage-related functions such as bone resorption, vascular development, and innate immunity. It signals through M-CSF R on monocytes, tissue macrophages, and osteoblasts. Both M-CSF and its receptor can be expressed by tumor cells, allowing M-CSF to act as an autocrine growth factor for cancer cells. Full length M-CSF is expressed as a transmembrane dimer, but various additional forms can be generated by alternative splicing, differential glycosylation, chondroitin sulfate proteoglycan modification, and proteolytic shedding.

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Analyzed by SEC-MALS

Analyzed by SEC-MALS,

Applications: WB, Neut
Reactivity: Mouse

Animal-Free.

Applications: WB, Neut
Reactivity: Mouse
Applications: WB, Neut
Reactivity: Human

Intended for preclinical researchers who may transition to GMP M-CSF for their clinical work

Applications: Neut
Reactivity: Mouse
Applications: WB, Neut
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: WB
Reactivity: Rat
Applications: WB, Neut
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: WB
Reactivity: Mouse
Applications: ICFlow
Reactivity: Human
Applications: WB, Neut
Reactivity: Mouse
Applications: ICFlow
Reactivity: Human
Applications: IHC, WB, ELISA
Reactivity: Human
Applications: CyTOF-ready, ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
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