MMP-12 Products
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
29 results for "MMP-12" in Products
29 results for "MMP-12" in Products
MMP-12 Products
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: MMP-12 Antibody [NBP1-31225]](https://resources.bio-techne.com/images/products/MMP-12-Antibody-Western-Blot-NBP1-31225-img0015.jpg "Western Blot: MMP-12 Antibody [NBP1-31225]")
| Source: | NS0 |
| Accession #: | P39900 |
| Applications: | EnzAct |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR03-23 |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
![Western Blot: MMP-12 Antibody (SR03-23) [NBP2-67344]](https://resources.bio-techne.com/images/products/MMP-12-Antibody-SR03-23-Western-Blot-NBP2-67344-img0005.jpg "Western Blot: MMP-12 Antibody (SR03-23) [NBP2-67344]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #82902 |
| Applications: | WB, IHC, IP, AP |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, IP |
Contains 4 membranes - each spotted in duplicate with 35 different protease antibodies
| Source: | NS0 |
| Accession #: | EDL24933 |
| Applications: | EnzAct |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #603E6.22 |
| Applications: | IHC, ELISA, IP |
![Immunohistochemistry-Frozen: MMP-12 Antibody (603E6.22) [DDX0280P-100]](https://resources.bio-techne.com/images/products/MMP-12-Antibody-603E6-22-Immunohistochemistry-Frozen-DDX0280P-100-img0007.jpg "Immunohistochemistry-Frozen: MMP-12 Antibody (603E6.22) [DDX0280P-100]")
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Source: | NS0 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #706F9.01 |
| Applications: | IHC, WB, ELISA, IP |
![Immunohistochemistry: MMP-12 Antibody (706F9.01) [DDX0281P-100]](https://resources.bio-techne.com/images/products/MMP-12-Antibody-706F9-01-Immunohistochemistry-DDX0281P-100-img0004.jpg "Immunohistochemistry: MMP-12 Antibody (706F9.01) [DDX0281P-100]")
| Reactivity: | Human, Canine |
| Details: | Mouse IgG1 Monoclonal Clone #703D10 |
| Applications: | IHC, ELISA, Flow |
![Immunohistochemistry: MMP-12 Antibody (703D10) [DDX0283P-100]](https://resources.bio-techne.com/images/products/MMP-12-Antibody-703D10-Immunohistochemistry-DDX0283P-100-img0005.jpg "Immunohistochemistry: MMP-12 Antibody (703D10) [DDX0283P-100]")
| Applications: | ELISA |
![ELISA: MMP-12 ELISA Development Kit [DDXK-E-MMP12-1]](https://resources.bio-techne.com/images/products/MMP-12-ELISA-Kit-ELISA-DDXK-E-MMP12-1-img0009.jpg "ELISA: MMP-12 ELISA Development Kit [DDXK-E-MMP12-1]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #701E4.03 |
| Applications: | WB, ELISA, IP |
![ELISA: MMP-12 Antibody (701E4.03) [DDX0284P-100]](https://resources.bio-techne.com/images/products/MMP-12-Antibody-701E4-03-ELISA-DDX0284P-100-img0002.jpg "ELISA: MMP-12 Antibody (701E4.03) [DDX0284P-100]")
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #RM381 |
| Applications: | IHC, WB |
| Applications: | ELISA |
| Applications: | ELISA |
Broad spectrum MMP inhibitor
| Chemical Name: | N-[(4'-Bromo[1,1'-biphenyl]-4-yl)sulfonyl]-L-valine |
| Purity: | ≥99% (HPLC) |
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2G3 |
| Applications: | IHC, WB, ELISA |
Highly selective MMP-3 and MMP-12 inhibitor
| Chemical Name: | (βR)-β-[[[(1S)-1-[[[(1S)-2-Methoxy-1-phenylethyl]amino]carbonyl]-2,2-dimethylpropyl]amino]carbonyl]-2-methyl-[1,1'-biphenyl]-4-hexanoic acid |
| Purity: | ≥95% (HPLC) |
Contains 4 membranes-2 spotted in duplicate with antibodies against 35 different proteases and 2 spotted in duplicate with antibodies against 32 different protease inhibitors
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
