Nephrin Products
Nephrin, also known as renal glomerulus-specific cell adhesion receptor and nephrosis 1 (NPHS1) is a 185 - 200 kDa type I transmembrane protein belonging to the immunoglobulin (Ig) superfamily. It is expressed on podocytes and is an essential component of the interpodocyte-spanning slit diaphragm complex. Nephrin forms cis-hetero-oligomeric complexes with Neph1, followed by trans-homophilic interaction with Nephrin on opposing cells. Mutations in the Nephrin gene is the pathogenic cause of congenital nephrotic syndrome. Mature human Nephrin contains a 1033 aa extracellular region and a 165 aa cytoplasmic tail. One potential soluble splice form of nephrin is known where aas 1056 - 1095 are deleted, eliminating the transmembrane region. Over aa 23 - 1029, human Nephrin shares 84% and 89% aa identity with mouse and canine Nephrin, respectively.
78 results for "Nephrin" in Products
78 results for "Nephrin" in Products
Nephrin Products
Nephrin, also known as renal glomerulus-specific cell adhesion receptor and nephrosis 1 (NPHS1) is a 185 - 200 kDa type I transmembrane protein belonging to the immunoglobulin (Ig) superfamily. It is expressed on podocytes and is an essential component of the interpodocyte-spanning slit diaphragm complex. Nephrin forms cis-hetero-oligomeric complexes with Neph1, followed by trans-homophilic interaction with Nephrin on opposing cells. Mutations in the Nephrin gene is the pathogenic cause of congenital nephrotic syndrome. Mature human Nephrin contains a 1033 aa extracellular region and a 165 aa cytoplasmic tail. One potential soluble splice form of nephrin is known where aas 1056 - 1095 are deleted, eliminating the transmembrane region. Over aa 23 - 1029, human Nephrin shares 84% and 89% aa identity with mouse and canine Nephrin, respectively.
Reactivity: | Human |
Details: | Sheep IgG Polyclonal |
Applications: | WB, Simple Western, IHC |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | IHC |
Source: | NS0 |
Accession #: | NP_062332 |
Applications: | BA |
Source: | NS0 |
Accession #: | O60500 |
Applications: | BA |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, ELISA |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #1037720 |
Applications: | WB |
Assay Range: | 156 - 10,000 pg/mL |
Applications: | ELISA |
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #2795E |
Applications: | IHC |
Reactivity: | Human |
Details: | Sheep IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Mouse IgG2a Kappa Monoclonal Clone #C7 |
Applications: | IHC |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #C9 |
Applications: | IHC |
Applications: | AC |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, ELISA |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, ELISA |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, ELISA |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
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