NT-4 Products
Neurotrophin-3 (NT-3) and Neurotrophin-4 (NT-4) are members of the NGF family of neurotrophic factors that are required for the differentiation and survival of specific neuronal subpopulations. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT-3, and NT-4/5. These secreted cytokines are synthesized as prepropeptides that are proteolytically processed to generate active propeptides and mature protein homodimers. Mature NT-4 also forms heterodimers with BDNF or NT-3. Neurotrophins induce dimerization and activation of Trk family receptors and promote the development and survival of selected peripheral and CNS neurons. All neurotrophins have six conserved disulfide-linked cysteine residues.
26 results for "NT-4" in Products
26 results for "NT-4" in Products
NT-4 Products
Neurotrophin-3 (NT-3) and Neurotrophin-4 (NT-4) are members of the NGF family of neurotrophic factors that are required for the differentiation and survival of specific neuronal subpopulations. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT-3, and NT-4/5. These secreted cytokines are synthesized as prepropeptides that are proteolytically processed to generate active propeptides and mature protein homodimers. Mature NT-4 also forms heterodimers with BDNF or NT-3. Neurotrophins induce dimerization and activation of Trk family receptors and promote the development and survival of selected peripheral and CNS neurons. All neurotrophins have six conserved disulfide-linked cysteine residues.
Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies
| Source: | Sf 21 (baculovirus) |
| Accession #: | P34130 |
| Applications: | BA |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #36526 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2E8 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: NT-4 Antibody (OTI2E8) [NBP1-47897]](https://resources.bio-techne.com/images/products/NT-4-Antibody-2E8-Western-Blot-NBP1-47897-img0028.jpg "Western Blot: NT-4 Antibody (OTI2E8) [NBP1-47897]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #36507 |
| Applications: | WB |
| Source: | NS0 |
| Accession #: | Q80VU4 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: NT-4 Antibody [NBP1-20951]](https://resources.bio-techne.com/images/products/NT-4-Antibody-Western-Blot-NBP1-20951-img0003.jpg "Western Blot: NT-4 Antibody [NBP1-20951]")
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #1G12 |
| Applications: | ELISA, Func |
![Proximity Ligation Assay: NT-4 Antibody (1G12) [H00004909-M02]](https://resources.bio-techne.com/images/products/NT-4-Antibody-1G12-Proximity-Ligation-Assay-H00004909-M02-img0001.jpg "Proximity Ligation Assay: NT-4 Antibody (1G12) [H00004909-M02]")
| Applications: | AC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: NT-4 Antibody [NBP1-59313]](https://resources.bio-techne.com/images/products/Neurotrophin-4-Antibody-Western-Blot-NBP1-59313-img0002.jpg "Western Blot: NT-4 Antibody [NBP1-59313]")
| Applications: | WB |
![Western Blot: NT-4 Overexpression Lysate [NBL1-13830]](https://resources.bio-techne.com/images/products/Neurotrophin-4-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-13830-img0002.jpg "Western Blot: NT-4 Overexpression Lysate [NBL1-13830]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: NT-4 Antibody [NBP2-58130]](https://resources.bio-techne.com/images/products/NT-4-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-58130-img0001.jpg "Immunocytochemistry/ Immunofluorescence: NT-4 Antibody [NBP2-58130]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2E8 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2E8 |
| Applications: | IHC, WB, ICC/IF |
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| Applications: | Bioactivity, PAGE |
![SDS-PAGE: Recombinant Human NT-4 Protein [NBP2-35106]](https://resources.bio-techne.com/images/products/Human-NT-4-Protein-SDS-Page-NBP2-35106-img0001.jpg "SDS-PAGE: Recombinant Human NT-4 Protein [NBP2-35106]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2E8 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2E8 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2E8 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2E8 |
| Applications: | IHC, WB, ICC/IF |