Pygopus-2 Products
Pygopus-1 and -2 are nuclear transcription co-activators. Structurally they are characterized by an N-terminal homology domain and C-terminal PHD (plant homeodomain) finger Zn2+-binding domain. The PHD finger binds to legless/Bcl9, which in turn binds beta-catenin, a downstream mediator of Wnt signaling. This complex binds TCF/LEF DNA binding proteins. Formation of the quaternary complex is required for the activation of Wnt-responsive genes.
45 results for "Pygopus-2" in Products
45 results for "Pygopus-2" in Products
Pygopus-2 Products
Pygopus-1 and -2 are nuclear transcription co-activators. Structurally they are characterized by an N-terminal homology domain and C-terminal PHD (plant homeodomain) finger Zn2+-binding domain. The PHD finger binds to legless/Bcl9, which in turn binds beta-catenin, a downstream mediator of Wnt signaling. This complex binds TCF/LEF DNA binding proteins. Formation of the quaternary complex is required for the activation of Wnt-responsive genes.
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #539730 |
| Applications: | WB, Simple Western, IHC, ICC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, IP, ChIP |
![Western Blot: Pygopus-2 Antibody [NBP2-20019]](https://resources.bio-techne.com/images/products/Pygopus-2-Antibody-Western-Blot-NBP2-20019-img0009.jpg "Western Blot: Pygopus-2 Antibody [NBP2-20019]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Zebrafish, Fish - Danio rerio (Zebrafish) |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP, ChIP |
![Western Blot: Pygopus-2 Antibody [NBP1-46171]](https://resources.bio-techne.com/images/products/Pygopus-2-Antibody-Western-Blot-NBP1-46171-img0004.jpg "Western Blot: Pygopus-2 Antibody [NBP1-46171]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #SR1693 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: Pygopus-2 Antibody [NBP2-20020]](https://resources.bio-techne.com/images/products/Pygopus-2-Antibody-Western-Blot-NBP2-20020-img0007.jpg "Western Blot: Pygopus-2 Antibody [NBP2-20020]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, WB (-) |
![Immunohistochemistry: Pygopus-2 Antibody [NBP1-46172]](https://resources.bio-techne.com/images/products/Pygopus-2-Antibody-Immunohistochemistry-NBP1-46172-img0005.jpg "Immunohistochemistry: Pygopus-2 Antibody [NBP1-46172]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: Pygopus-2 Antibody [NBP2-20018]](https://resources.bio-techne.com/images/products/Pygopus-2-Antibody-Western-Blot-NBP2-20018-img0002.jpg "Western Blot: Pygopus-2 Antibody [NBP2-20018]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Pygopus-2 Antibody [NBP1-87548]](https://resources.bio-techne.com/images/products/Pygopus-2-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-87548-img0006.jpg "Immunocytochemistry/ Immunofluorescence: Pygopus-2 Antibody [NBP1-87548]")
| Applications: | WB |
| Applications: | WB, ELISA, MA, AP |
| Applications: | WB, ELISA, MA, AP, PAGE |
![SDS-PAGE: Recombinant Human Pygopus-2 GST (N-Term) Protein [H00090780-Q01]](https://resources.bio-techne.com/images/products/qc_test-H00090780-Q01-1.jpg "SDS-PAGE: Recombinant Human Pygopus-2 GST (N-Term) Protein [H00090780-Q01]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/Immunofluorescence: Pygopus-2 Antibody [NBP3-21376] -](https://resources.bio-techne.com/images/products/nbp3-21376_rabbit-pygopus-2-pab-45202315531349.jpg "Immunocytochemistry/Immunofluorescence: Pygopus-2 Antibody [NBP3-21376] -")
| Applications: | AC |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB (-) |