5-HT1B Products
5-HT1B is a 7TM receptor for serotonin and is expressed on striatal neurons and Purkinje cells in the cerebellum. 5-HT1B ligation inhibits glycinergic signaling, appetite, circadian rhythym light responsiveness, and trigeminal-mediated nociception. It is an important pharmacologic target in the treatment of migrane headaches.
27 results for "5-HT1B" in Products
27 results for "5-HT1B" in Products
5-HT1B Products
5-HT1B is a 7TM receptor for serotonin and is expressed on striatal neurons and Purkinje cells in the cerebellum. 5-HT1B ligation inhibits glycinergic signaling, appetite, circadian rhythym light responsiveness, and trigeminal-mediated nociception. It is an important pharmacologic target in the treatment of migrane headaches.
Endogenous 5-HT receptor agonist
| Alternate Names: | 5-Hydroxytryptamine,5-HT |
| Chemical Name: | 3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride |
| Purity: | ≥98% (HPLC) |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% (HPLC) |
5-HT1A, 5-HT1B and 5-HT1D agonist
| Alternate Names: | GR 43175 |
| Chemical Name: | 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate |
| Purity: | ≥99% (HPLC) |
Potent and selective 5-HT1B and 5-HT1D antagonist
| Chemical Name: | N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-carboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective h5-HT1B antagonist
| Chemical Name: | N-[3-[3-(Dimethylamino)ethoxy]-4-methoxyphenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
5-HT1B agonist
| Chemical Name: | 1,4-Dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrol[3,2-b]pyridin-5-one dihydrochloride |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #499325 |
| Applications: | IHC |
Potent and selective 5-HT1B agonist
| Chemical Name: | 5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine hydrochloride |
| Purity: | ≥98% (HPLC) |
5-HT1B antagonist
| Chemical Name: | 3-[3-(Dimethylamino)propyl]-4-hydroxy-N-[4-(4-pyridinyl)phenyl]benzamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Selective 5-HT1B antagonist
| Chemical Name: | 1'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine hydrochloride |
| Purity: | ≥95% (HPLC) |
α partial agonist; also D2-like partial agonist and 5-HT antagonist
| Chemical Name: | 9,10-Dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotaman-3',6',18-trione mesylate |
| Purity: | ≥98% (HPLC) |
5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist
| Chemical Name: | 4-[3-[tert-Butylamino]-2-hydroxypropoxy]-1H-indole-2-carbonitrile hemifumarate |
| Purity: | ≥98% (HPLC) |
Potent 5-HT1B/1D/1F agonist
| Chemical Name: | (4S)-4-((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)-2-oxazolidinone |
| Purity: | ≥99% (HPLC) |
Highly potent 5-HT1B agonist; also 5-HT3 antagonist
| Chemical Name: | 6-Chloro-2-[piperidinyl-4-thio]pyridine hydrochloride |
| Purity: | ≥99% (HPLC) |
5-HT1B agonist
| Chemical Name: | 7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo[1,2-a]-quinoxaline dimaleate |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: 5-HT1B Antibody [NB100-56350]](https://resources.bio-techne.com/images/products/5-HT1B-Antibody-Western-Blot-NB100-56350-img0004.jpg "Western Blot: 5-HT1B Antibody [NB100-56350]")
Inhibits calcium-sensitive chloride currents
| Chemical Name: | 5-Nitro-2-(3-phenylpropylamino)benzoic acid |
| Purity: | ≥99% (HPLC) |
5-HT1A and 5-HT1B agonist
| Chemical Name: | 5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole hemisuccinate |
| Purity: | ≥99% (HPLC) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF, IHC |
Selective 5-ht5a antagonist
| Chemical Name: | N-[2-(Dimethylamino)ethyl]-N-[[4'-[[(2-phenylethyl)amino]methyl][1,1'-biphenyl]-4-yl]methyl]cyclopentanepropanamide dihydrochloride |
| Purity: | ≥99% (HPLC) |
| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: 5-HT1B Antibody - BSA Free [NBP3-06662]](https://resources.bio-techne.com/images/products/5-HT1B-Antibody-Immunohistochemistry-Paraffin-NBP3-06662-img0002.jpg "Immunohistochemistry-Paraffin: 5-HT1B Antibody - BSA Free [NBP3-06662]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit Polyclonal |
| Applications: | WB, ELISA, IP |
| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | WB |
![Western Blot: 5-HT1B Antibody [NBP2-86927]](https://resources.bio-techne.com/images/products/5-HT1B-Antibody-Western-Blot-NBP2-86927-img0001.jpg "Western Blot: 5-HT1B Antibody [NBP2-86927]")
| Applications: | WB |
![Western Blot: 5-HT1B Overexpression Lysate [NBL1-11775]](https://resources.bio-techne.com/images/products/5HT1B-Receptor-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-11775-img0002.jpg "Western Blot: 5-HT1B Overexpression Lysate [NBL1-11775]")