AAK1 Products
AP2-associated protein kinase 1 (AAK1) is a 100 kDa intracellular kinase that binds and phosphorylates NUMB and the mu2 subunit of AP2. NUMB and AP2 are adaptor proteins which are involved in the assembly and sorting of clathrin coated pits during receptor-mediated endocytosis. AAK1 contains one catalytic domain (aa 46-315) and a C-terminal clathrin-binding region. Alternate splicing of human AAK1 generates a 145 kDa long isoform that contains an additional clathrin-binding domain.
71 results for "AAK1" in Products
71 results for "AAK1" in Products
AAK1 Products
AP2-associated protein kinase 1 (AAK1) is a 100 kDa intracellular kinase that binds and phosphorylates NUMB and the mu2 subunit of AP2. NUMB and AP2 are adaptor proteins which are involved in the assembly and sorting of clathrin coated pits during receptor-mediated endocytosis. AAK1 contains one catalytic domain (aa 46-315) and a C-terminal clathrin-binding region. Alternate splicing of human AAK1 generates a 145 kDa long isoform that contains an additional clathrin-binding domain.
AAK1 and BMP2K inhibitor; activates Wnt signaling
| Chemical Name: | N-(6-(3-((N,N-diethylsulfamoyl)amino)phenyl)-1H-indazol-3-yl)cyclopropanecarboxamide |
| Purity: | ≥98% (HPLC) |
Negative control for SGC AAK1 1 (Cat.No. 6528)
| Chemical Name: | N-[6-[3-[(Cyclopropylsulfonyl)amino]phenyl]-1H-indazol-3-yl]-2-methylpropanamide |
| Purity: | ≥97% (HPLC) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunohistochemistry-Paraffin: AAK1 Antibody [NBP1-84110]](https://resources.bio-techne.com/images/products/AAK1-Antibody-Immunohistochemistry-Paraffin-NBP1-84110-img0009.jpg "Immunohistochemistry-Paraffin: AAK1 Antibody [NBP1-84110]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #702425 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: AAK1 Antibody [NBP1-84111]](https://resources.bio-techne.com/images/products/AAK1-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-84111-img0011.jpg "Immunocytochemistry/ Immunofluorescence: AAK1 Antibody [NBP1-84111]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: AAK1 AntibodyBSA Free [NBP1-77335]](https://resources.bio-techne.com/images/products/AAK1-Antibody-Western-Blot-NBP1-77335-img0003.jpg "Western Blot: AAK1 AntibodyBSA Free [NBP1-77335]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #4B10 |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: AAK1 Antibody (4B10) [H00022848-M02]](https://resources.bio-techne.com/images/products/AAK1-Antibody-4B10-Western-Blot-H00022848-M02-img0005.jpg "Western Blot: AAK1 Antibody (4B10) [H00022848-M02]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: AAK1 AntibodyBSA Free [NBP1-76343]](https://resources.bio-techne.com/images/products/AAK1-Antibody-Western-Blot-NBP1-76343-img0002.jpg "Western Blot: AAK1 AntibodyBSA Free [NBP1-76343]")
| Applications: | WB, ELISA, MA, AP |
![SDS-PAGE: Recombinant Human AAK1 GST (N-Term) Protein [H00022848-P01]](https://resources.bio-techne.com/images/products/Recombinant-Human-AAK1-Protein-SDS-Page-H00022848-P01-img0002.jpg "SDS-PAGE: Recombinant Human AAK1 GST (N-Term) Protein [H00022848-P01]")
| Applications: | WB, ELISA, MA, AP |
| Applications: | WB |
![Western Blot: AAK1 293T Cell Transient Overexpression Lysate [H00022848-T01]](https://resources.bio-techne.com/images/products/AAK1-Overexpression-Lysate-Western-Blot-H00022848-T01-img0002.jpg "Western Blot: AAK1 293T Cell Transient Overexpression Lysate [H00022848-T01]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: AAK1 Antibody [NBP1-45214]](https://resources.bio-techne.com/images/products/AAK1-Antibody-Western-Blot-NBP1-45214-img0002.jpg "Western Blot: AAK1 Antibody [NBP1-45214]")
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: AAK1 Antibody [NBP1-79574]](https://resources.bio-techne.com/images/products/AAK1-Antibody-Western-Blot-NBP1-79574-img0001.jpg "Western Blot: AAK1 Antibody [NBP1-79574]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA |
| Applications: | AC |
| Applications: | AC |
| Applications: | AC |
| Applications: | AC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA |