BACE-2 Products
Both BACE-1 and BACE-2 are membrane-bound aspartic proteases of the pepsin family. BACE-1 is a potential target for treatment of Alzheimer's disease because it is the principle b-secretase responsible for cleavage of amyloid precursor protein (APP). BACE-2 differs from BACE-1 in several aspects including pro-enzyme activation, substrate binding sites, transcriptional regulation, and function in A beta peptide production.
74 results for "BACE-2" in Products
74 results for "BACE-2" in Products
BACE-2 Products
Both BACE-1 and BACE-2 are membrane-bound aspartic proteases of the pepsin family. BACE-1 is a potential target for treatment of Alzheimer's disease because it is the principle b-secretase responsible for cleavage of amyloid precursor protein (APP). BACE-2 differs from BACE-1 in several aspects including pro-enzyme activation, substrate binding sites, transcriptional regulation, and function in A beta peptide production.
BACE1 and BACE2 inhibitor
| Chemical Name: | N-[3-[(5R)-3-Amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IP |
| Source: | NS0 |
| Accession #: | Q9Y5Z0-1 |
| Applications: | EnzAct |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #391017 |
| Applications: | IHC |
| Source: | NS0 |
| Accession #: | Q9JL18 |
| Applications: | EnzAct |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: BACE-2 Antibody [NBP2-15539]](https://resources.bio-techne.com/images/products/BACE2-Antibody-Western-Blot-NBP2-15539-img0001.jpg "Western Blot: BACE-2 Antibody [NBP2-15539]")
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
![Western Blot: BACE-2 AntibodyBSA Free [NBP1-77309]](https://resources.bio-techne.com/images/products/BACE-2-Antibody-Western-Blot-NBP1-77309-img0002.jpg "Western Blot: BACE-2 AntibodyBSA Free [NBP1-77309]")
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
![Western Blot: BACE-2 AntibodyBSA Free [NBP1-77308]](https://resources.bio-techne.com/images/products/BACE-2-Antibody-Western-Blot-NBP1-77308-img0004.jpg "Western Blot: BACE-2 AntibodyBSA Free [NBP1-77308]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1/ 9 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: BACE-2 Antibody (1/ 9)Azide and BSA Free [NBP2-81075]](https://resources.bio-techne.com/images/products/BACE-2-Antibody-1-9-Western-Blot-NBP2-81075-img0002.jpg "Western Blot: BACE-2 Antibody (1/ 9)Azide and BSA Free [NBP2-81075]")
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: BACE-2 Antibody [NBP2-68624]](https://resources.bio-techne.com/images/products/BACE-2-Antibody-Western-Blot-NBP2-68624-img0001.jpg "Western Blot: BACE-2 Antibody [NBP2-68624]")
Potent and selective β-secretase (BACE) inhibitor
| Chemical Name: | N-[3-[(4aS,7aS)-2-Amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
| Applications: | AC |
![Western Blot: BACE-2 Antibody Blocking Peptide [NBP1-77308PEP]](https://resources.bio-techne.com/images/products/BACE2-Peptide-Western-Blot-NBP1-77308PEP-img0001.jpg "Western Blot: BACE-2 Antibody Blocking Peptide [NBP1-77308PEP]")
| Applications: | AC |
| Applications: | AC |
| Applications: | WB |
![Western Blot: BACE-2 Overexpression Lysate [NBP2-09973]](https://resources.bio-techne.com/images/products/BACE2-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-09973-img0001.jpg "Western Blot: BACE-2 Overexpression Lysate [NBP2-09973]")
| Applications: | WB |
![Western Blot: BACE-2 Overexpression Lysate [NBP2-07491]](https://resources.bio-techne.com/images/products/BACE2-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-07491-img0001.jpg "Western Blot: BACE-2 Overexpression Lysate [NBP2-07491]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1/ 9 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA |