30 results for "BRD2" in Products
BRD2 Products
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, IP, Func |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #JG40-42 |
Applications: | IHC, WB, ICC/IF, Flow |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, KD |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF, IP |
Reactivity: | Human, Rat |
Details: | Mouse IgG2B Monoclonal Clone #7C1B10 |
Applications: | WB, ELISA, Flow |
Recombinant Monoclonal Antibody.
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Monoclonal Clone #BL-167-2A2 |
Applications: | WB, Flow, IP |
Reactivity: | Human |
Details: | Mouse IgG2b Kappa Monoclonal Clone #3D10 |
Applications: | WB, ELISA |
Reactivity: | Mouse |
Details: | Rabbit Polyclonal |
Applications: | WB, ELISA |
Applications: | PAGE |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #12C2E4 |
Applications: | WB, IP |
Applications: | WB |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | ICC/IF |
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Monoclonal Clone #5K5Y6 |
Applications: | WB, ELISA |
Applications: | AC |
Potent and high affinity BET bromodomain inhibitor; anti-inflammatory; orally bioavailable.
Alternate Names: | GSK525762A,Molibresib |
Chemical Name: | (4S)-6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide |
Purity: | ≥98% (HPLC) |
Potent and selective BET bromodomain inhibitor; cell permeable
Chemical Name: | (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester |
Purity: | ≥98% (HPLC) |
BET bromodomain inhibitor; orally bioavailable
Alternate Names: | Birabresib |
Chemical Name: | (6S)-4-(4-Chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide |
Purity: | ≥98% (HPLC) |
(+)-JQ1 based Degrader (PROTAC®) that preferentially degrades BRD4
Chemical Name: | (2S,4R)-1-((S)-2-(tert-butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecanoyl)- 4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
Purity: | ≥98% (HPLC) |
Photoswitchable BET bromodomain Degrader (PHOTAC)
Chemical Name: | 2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f]-[1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-(2-(4-((E)-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)diazenyl)-2,6-dimethoxyphenoxy)acetamido)butyl)acetamide |
Purity: | ≥98% (HPLC) |
BET bromodomain inhibitor; also promotes differentiation of hiPSCs into megakaryocytes
Chemical Name: | 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydroxy-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one dihydrochloride |
Purity: | ≥98% (HPLC) |
Potent and selective trivalent BET Bromodomain Degrader (PROTAC®)
Chemical Name: | N,N'-(11-((2-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)methyl)-11-methyl-3,6,9,13,16,19-hexaoxahenicosane-1,21-diyl)bis(2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamide) |
Purity: | ≥98% (HPLC) |
BET bromodomain inhibitor; arrests cell cycle at G1 phase
Alternate Names: | TEN 010 |
Chemical Name: | (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide |
Purity: | ≥98% (HPLC) |
Negative control for SIM1 (Cat. No. 7432)
Chemical Name: | N,N'-(11-((2-(((S)-1-((2S,4S)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)methyl)-11-methyl-3,6,9,13,16,19-hexaoxahenicosane-1,21-diyl)bis(2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamide) |
Purity: | ≥98% (HPLC) |
Broad spectrum bromodomain inhibitor
Chemical Name: | N-[(6-3-Methanesulfonamido-4-methylphenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]carbamate |
Purity: | ≥98% (HPLC) |
Potent BET bromodomain PROTAC®; also degrades BRD-tagged chimeric antigen receptors (CAR) in T cells
Chemical Name: | (2S,4R)-1-((S)-2-(tert-Butyl)-15-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,14-dioxo-6,10-dioxa-3,13-diazapentadecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide |
Purity: | ≥98% (HPLC) |